STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nanAN-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. (292 aa)    
Predicted Functional Partners:
nanE
N-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).
 
  
 0.982
nanK
Bifunctional protein: N-acetyl mannosamine kinase, ROK family; transcription regulator.
 
  
 0.980
lp_3566
N-acetylglucosamine 2-epimerase.
 
  
 0.944
lp_3563
Sodium-coupled N-acetylneuraminate transporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
  
 0.926
citX
Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase.
   
    0.720
citF
Citrate lyase, alpha chain.
   
    0.712
lp_3562
Lipase/esterase.
  
  
 0.710
lp_3576
Hypothetical protein.
      
 0.701
lp_3570
Transposase.
  
  
 0.695
nagB
Glucosamine-6-phosphate isomerase/deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
  
  
 0.691
Your Current Organism:
Lactobacillus plantarum
NCBI taxonomy Id: 220668
Other names: L. plantarum WCFS1, Lactobacillus plantarum WCFS1, Lactobacillus plantarum str. WCFS1, Lactobacillus plantarum strain WCFS1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.