Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
spx5RNA polymerase (RNAP)-binding regulatory protein, arsenate reductase (ArsC) family, Spx subfamily; Belongs to the ArsC family. (145 aa)    
Predicted Functional Partners:
lamA
Two-component system response regulator; accesory gene regulator protein A.
 
    0.836
lp_2224
Dithiol-disulfide isomerase, DsbA family,FrnE-like subfamily.
  
 
 0.627
recU
Recombinase; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family.
  
     0.617
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.596
lamC
Two-component system histidine protein kinase; sensor protein.
 
  
 0.538
lp_2061
Hypothetical protein.
  
    0.535
dnaI
Primosomal protein DnaI.
  
     0.492
rpmE
50S ribosomal protein L31; Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
  
  
 0.467
trxH
Thioredoxin H-type.
   
  
 0.465
nrdH
Glutaredoxin-like protein nrdH.
      
 0.457
Your Current Organism:
Lactobacillus plantarum
NCBI taxonomy Id: 220668
Other names: L. plantarum WCFS1, Lactobacillus plantarum WCFS1, Lactobacillus plantarum str. WCFS1, Lactobacillus plantarum strain WCFS1
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