STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLT17129.1RNA polymerase sigma factor SigX; Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in B. subtilis has been shown to regulate cell envelope modification and may effect antibiotic resistance; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (183 aa)    
Predicted Functional Partners:
KLT17130.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   0.896
KLT17676.1
RNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.756
KLT17131.1
Peptidase, M23/M37 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.617
KLT16073.1
Anti-sigma W factor; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.577
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.550
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.529
KLT17128.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.525
KLT19373.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.467
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.453
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.452
Your Current Organism:
Bacillus vireti
NCBI taxonomy Id: 220686
Other names: B. vireti, Bacillus vireti Heyrman et al. 2004, DSM 15602, JCM 21711, LMG 21834, LMG:21834, NBRC 102452, strain IDA3632, strain R-15447
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.