STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spxA-2ArsR family transcriptional regulator; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. (131 aa)    
Predicted Functional Partners:
KLT15658.1
Rrf2 family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.862
KLT19260.1
Dithiol-disulfide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.858
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.839
KLT18818.1
Dithiol-disulfide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.834
sigA
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
   0.830
KLT15659.1
Group-specific protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.830
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.827
KLT15605.1
DSBA oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.740
KLT19376.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0356 family.
  
 
   0.718
KLT16239.1
General stress protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.718
Your Current Organism:
Bacillus vireti
NCBI taxonomy Id: 220686
Other names: B. vireti, Bacillus vireti Heyrman et al. 2004, DSM 15602, JCM 21711, LMG 21834, LMG:21834, NBRC 102452, strain IDA3632, strain R-15447
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