STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORW74072.1Type VII secretion AAA-ATPase EccA; Derived by automated computational analysis using gene prediction method: Protein Homology. (603 aa)    
Predicted Functional Partners:
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
  0.814
prcA
Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family.
   
 0.797
prcB
Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.
   
 0.797
ORW70768.1
Acetoin utilization protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.793
ORW72098.1
Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.756
ORW72202.1
ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.733
ORW72187.1
ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.733
ORW74108.1
Secretion protein EspI; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.727
htpG
Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity.
   
 0.711
arc
Proteasome ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
  
  0.699
Your Current Organism:
Mycobacterium saskatchewanense
NCBI taxonomy Id: 220927
Other names: ATCC BAA-544, CIP 108114, DSM 44616, JCM 13016, M. saskatchewanense, Mycobacterium saskatchewanense Turenne et al. 2004, strain 00-250
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