Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ORW70432.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (853 aa)    
Predicted Functional Partners:
ORW70431.1
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
kdpC
K+-transporting ATPase subunit C; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
 
  
 0.996
kdpB
Potassium transporter KtrB; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
 
  
 0.991
kdpA
Potassium-transporting ATPase subunit A; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.
 
  
 0.989
ORW72261.1
Stage II sporulation protein E; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.841
ORW68049.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.841
ORW74046.1
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.805
ORW63983.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.767
ORW71372.1
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.707
ORW70746.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.667
Your Current Organism:
Mycobacterium saskatchewanense
NCBI taxonomy Id: 220927
Other names: ATCC BAA-544, CIP 108114, DSM 44616, JCM 13016, M. saskatchewanense, Mycobacterium saskatchewanense Turenne et al. 2004, strain 00-250
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