Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lntAcyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (527 aa)    
Predicted Functional Partners:
AIN93569.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.746
cmk
30S ribosomal protein S1; Proteins from Treponema appear to be a fusion of cytidylate kinase and multiple (up to 6) S1 domains; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.665
AIN92974.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.619
AIN92991.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.615
AIN92992.1
Galactokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GHMP kinase family.
       0.594
AIN92990.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.592
AIN94829.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.588
AIN92989.1
Phosphoglycolate phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.523
lspA
Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
 
   
 0.513
yidC
Insertase; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
  
   
 0.463
Your Current Organism:
Treponema putidum
NCBI taxonomy Id: 221027
Other names: ATCC 700334, CIP 108088, OMZ 758, T. putidum, Treponema putidum Wyss et al. 2004, strain JZC3
Server load: medium (78%) [HD]