Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AIN94049.1Dihydroorotate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (591 aa)    
Predicted Functional Partners:
AIN92890.1
Dihydroorotase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
pyrB
Aspartate carbamoyltransferase; Catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.999
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
 0.999
AIN92893.1
Orotidine 5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.993
AIN92924.1
Uracil permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.972
AIN93323.1
ferredoxin-NADP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.954
AIN94612.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.950
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
 
 
 0.948
purM
Phosphoribosylaminoimidazole synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.943
AIN93322.1
Dihydropyrimidine dehydrogenase; NADH-dependent; catalyzes the conversion of pyrimidines to 5,6-dihydro compounds in pyrimidine degradation; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.925
Your Current Organism:
Treponema putidum
NCBI taxonomy Id: 221027
Other names: ATCC 700334, CIP 108088, OMZ 758, T. putidum, Treponema putidum Wyss et al. 2004, strain JZC3
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