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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (234 aa)    
Predicted Functional Partners:
AIN94049.1
Dihydroorotate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
AIN92893.1
Orotidine 5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.992
AIN92890.1
Dihydroorotase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.971
pyrB
Aspartate carbamoyltransferase; Catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.950
AIN92924.1
Uracil permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.885
AIN93415.1
Phosphoribosylpyrophosphate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribose-phosphate pyrophosphokinase family.
  
 
 0.878
AIN93323.1
ferredoxin-NADP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.841
purM
Phosphoribosylaminoimidazole synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.812
gatA
glutamyl-tRNA amidotransferase; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).
  
    0.713
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
 
  
 0.703
Your Current Organism:
Treponema putidum
NCBI taxonomy Id: 221027
Other names: ATCC 700334, CIP 108088, OMZ 758, T. putidum, Treponema putidum Wyss et al. 2004, strain JZC3
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