Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AIN94298.1DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)    
Predicted Functional Partners:
AIN94779.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.590
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.584
AIN94300.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.563
AIN93434.1
Diguanylate phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.559
nnrD
Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...]
     
 0.559
AIN94203.1
protein-S-isoprenylcysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.547
purM
Phosphoribosylaminoimidazole synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.545
AIN94332.1
NAD synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD synthetase family.
  
  
 0.536
AIN93296.1
Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.534
AIN93057.1
Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.530
Your Current Organism:
Treponema putidum
NCBI taxonomy Id: 221027
Other names: ATCC 700334, CIP 108088, OMZ 758, T. putidum, Treponema putidum Wyss et al. 2004, strain JZC3
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