node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OB1696 | accC | gene:10733936 | gene:10734125 | Biotin carboxylase; CDS_ID OB1696. | acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.903 |
OB1696 | leuA | gene:10733936 | gene:10734872 | Biotin carboxylase; CDS_ID OB1696. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.946 |
OB2628 | ilvB | gene:10734880 | gene:10734875 | Branched-chain amino acid aminotransferase; CDS_ID OB2628. | Acetolactate synthase large subunit; CDS_ID OB2623. | 0.499 |
OB2628 | ilvC | gene:10734880 | gene:10734873 | Branched-chain amino acid aminotransferase; CDS_ID OB2628. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.544 |
OB2628 | ilvD | gene:10734880 | gene:10734876 | Branched-chain amino acid aminotransferase; CDS_ID OB2628. | Dihydroxy-acid dehydratase; CDS_ID OB2624; Belongs to the IlvD/Edd family. | 0.980 |
OB2628 | ilvN | gene:10734880 | gene:10734874 | Branched-chain amino acid aminotransferase; CDS_ID OB2628. | Acetolactate synthase small subunit; CDS_ID OB2622. | 0.554 |
OB2628 | leuA | gene:10734880 | gene:10734872 | Branched-chain amino acid aminotransferase; CDS_ID OB2628. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.965 |
OB2628 | leuC | gene:10734880 | gene:10734870 | Branched-chain amino acid aminotransferase; CDS_ID OB2628. | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.508 |
accC | OB1696 | gene:10734125 | gene:10733936 | acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Biotin carboxylase; CDS_ID OB1696. | 0.903 |
accC | leuA | gene:10734125 | gene:10734872 | acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.946 |
ilvB | OB2628 | gene:10734875 | gene:10734880 | Acetolactate synthase large subunit; CDS_ID OB2623. | Branched-chain amino acid aminotransferase; CDS_ID OB2628. | 0.499 |
ilvB | ilvC | gene:10734875 | gene:10734873 | Acetolactate synthase large subunit; CDS_ID OB2623. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.997 |
ilvB | ilvD | gene:10734875 | gene:10734876 | Acetolactate synthase large subunit; CDS_ID OB2623. | Dihydroxy-acid dehydratase; CDS_ID OB2624; Belongs to the IlvD/Edd family. | 0.967 |
ilvB | ilvN | gene:10734875 | gene:10734874 | Acetolactate synthase large subunit; CDS_ID OB2623. | Acetolactate synthase small subunit; CDS_ID OB2622. | 0.999 |
ilvB | leuA | gene:10734875 | gene:10734872 | Acetolactate synthase large subunit; CDS_ID OB2623. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.986 |
ilvB | leuB | gene:10734875 | gene:10734871 | Acetolactate synthase large subunit; CDS_ID OB2623. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. | 0.991 |
ilvB | leuC | gene:10734875 | gene:10734870 | Acetolactate synthase large subunit; CDS_ID OB2623. | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.902 |
ilvB | leuD | gene:10734875 | gene:10734869 | Acetolactate synthase large subunit; CDS_ID OB2623. | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.912 |
ilvC | OB2628 | gene:10734873 | gene:10734880 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Branched-chain amino acid aminotransferase; CDS_ID OB2628. | 0.544 |
ilvC | ilvB | gene:10734873 | gene:10734875 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Acetolactate synthase large subunit; CDS_ID OB2623. | 0.997 |