node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OB0424 | OB1220 | gene:10732627 | gene:10733459 | GTP cyclohydrolase II; CDS_ID OB0424. | GTP pyrophosphokinase; CDS_ID OB1220. | 0.800 |
OB0424 | OB1688 | gene:10732627 | gene:10733928 | GTP cyclohydrolase II; CDS_ID OB0424. | Hypothetical conserved protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.903 |
OB0424 | ndk | gene:10732627 | gene:10734027 | GTP cyclohydrolase II; CDS_ID OB0424. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.862 |
OB0424 | pykA | gene:10732627 | gene:10734419 | GTP cyclohydrolase II; CDS_ID OB0424. | Pyruvate kinase; CDS_ID OB2171; Belongs to the pyruvate kinase family. | 0.800 |
OB0424 | relA | gene:10732627 | gene:10734270 | GTP cyclohydrolase II; CDS_ID OB0424. | GTP pyrophosphokinase (stringent response); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.817 |
OB1130 | OB1220 | gene:10733369 | gene:10733459 | Hypothetical protein; CDS_ID OB1130. | GTP pyrophosphokinase; CDS_ID OB1220. | 0.585 |
OB1130 | trmE | gene:10733369 | gene:10735743 | Hypothetical protein; CDS_ID OB1130. | tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.720 |
OB1220 | OB0424 | gene:10733459 | gene:10732627 | GTP pyrophosphokinase; CDS_ID OB1220. | GTP cyclohydrolase II; CDS_ID OB0424. | 0.800 |
OB1220 | OB1130 | gene:10733459 | gene:10733369 | GTP pyrophosphokinase; CDS_ID OB1220. | Hypothetical protein; CDS_ID OB1130. | 0.585 |
OB1220 | OB1222 | gene:10733459 | gene:10733461 | GTP pyrophosphokinase; CDS_ID OB1220. | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.747 |
OB1220 | OB1688 | gene:10733459 | gene:10733928 | GTP pyrophosphokinase; CDS_ID OB1220. | Hypothetical conserved protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.800 |
OB1220 | gidA | gene:10733459 | gene:10735742 | GTP pyrophosphokinase; CDS_ID OB1220. | Glucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.659 |
OB1220 | ndk | gene:10733459 | gene:10734027 | GTP pyrophosphokinase; CDS_ID OB1220. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.900 |
OB1220 | ppnK | gene:10733459 | gene:10733460 | GTP pyrophosphokinase; CDS_ID OB1220. | Inorganic polyphosphonate:ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.817 |
OB1220 | pykA | gene:10733459 | gene:10734419 | GTP pyrophosphokinase; CDS_ID OB1220. | Pyruvate kinase; CDS_ID OB2171; Belongs to the pyruvate kinase family. | 0.900 |
OB1220 | relA | gene:10733459 | gene:10734270 | GTP pyrophosphokinase; CDS_ID OB1220. | GTP pyrophosphokinase (stringent response); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.918 |
OB1220 | trmE | gene:10733459 | gene:10735743 | GTP pyrophosphokinase; CDS_ID OB1220. | tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.749 |
OB1222 | OB1220 | gene:10733461 | gene:10733459 | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | GTP pyrophosphokinase; CDS_ID OB1220. | 0.747 |
OB1222 | ppnK | gene:10733461 | gene:10733460 | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Inorganic polyphosphonate:ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.803 |
OB1222 | trmE | gene:10733461 | gene:10735743 | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.783 |