node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OB1213 | OB1409 | gene:10733452 | gene:10733649 | Hypothetical conserved protein; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. | Hypothetical conserved protein; CDS_ID OB1409; Belongs to the UPF0356 family. | 0.730 |
OB1213 | OB1503 | gene:10733452 | gene:10733743 | Hypothetical conserved protein; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. | DNA-directed RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.696 |
OB1213 | OB2230 | gene:10733452 | gene:10734478 | Hypothetical conserved protein; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. | General stress protein; CDS_ID OB2230. | 0.698 |
OB1213 | rpoA | gene:10733452 | gene:10732335 | Hypothetical conserved protein; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. | DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.781 |
OB1213 | rpoB | gene:10733452 | gene:10732302 | Hypothetical conserved protein; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. | DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.635 |
OB1213 | rpoC | gene:10733452 | gene:10732303 | Hypothetical conserved protein; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. | DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.762 |
OB1213 | rpoE | gene:10733452 | gene:10735260 | Hypothetical conserved protein; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. | DNA-directed RNA polymerase delta chain; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. | 0.732 |
OB1213 | sigA | gene:10733452 | gene:10734190 | Hypothetical conserved protein; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. | RNA polymerase sigma-43(-A) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.766 |
OB1408 | OB1409 | gene:10733648 | gene:10733649 | Hypothetical conserved protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily. | Hypothetical conserved protein; CDS_ID OB1409; Belongs to the UPF0356 family. | 0.879 |
OB1408 | rpoB | gene:10733648 | gene:10732302 | Hypothetical conserved protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily. | DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.432 |
OB1408 | sigA | gene:10733648 | gene:10734190 | Hypothetical conserved protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily. | RNA polymerase sigma-43(-A) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.446 |
OB1409 | OB1213 | gene:10733649 | gene:10733452 | Hypothetical conserved protein; CDS_ID OB1409; Belongs to the UPF0356 family. | Hypothetical conserved protein; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. | 0.730 |
OB1409 | OB1408 | gene:10733649 | gene:10733648 | Hypothetical conserved protein; CDS_ID OB1409; Belongs to the UPF0356 family. | Hypothetical conserved protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily. | 0.879 |
OB1409 | OB1503 | gene:10733649 | gene:10733743 | Hypothetical conserved protein; CDS_ID OB1409; Belongs to the UPF0356 family. | DNA-directed RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.684 |
OB1409 | OB2230 | gene:10733649 | gene:10734478 | Hypothetical conserved protein; CDS_ID OB1409; Belongs to the UPF0356 family. | General stress protein; CDS_ID OB2230. | 0.647 |
OB1409 | OB2292 | gene:10733649 | gene:10734540 | Hypothetical conserved protein; CDS_ID OB1409; Belongs to the UPF0356 family. | Hypothetical conserved protein; CDS_ID OB2292. | 0.635 |
OB1409 | rpoA | gene:10733649 | gene:10732335 | Hypothetical conserved protein; CDS_ID OB1409; Belongs to the UPF0356 family. | DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.766 |
OB1409 | rpoB | gene:10733649 | gene:10732302 | Hypothetical conserved protein; CDS_ID OB1409; Belongs to the UPF0356 family. | DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.766 |
OB1409 | rpoC | gene:10733649 | gene:10732303 | Hypothetical conserved protein; CDS_ID OB1409; Belongs to the UPF0356 family. | DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.766 |
OB1409 | rpoE | gene:10733649 | gene:10735260 | Hypothetical conserved protein; CDS_ID OB1409; Belongs to the UPF0356 family. | DNA-directed RNA polymerase delta chain; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. | 0.777 |