node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFC38981.1 | SFC95233.1 | SAMN04489722_102338 | SAMN04489722_104138 | GMP synthase (glutamine-hydrolysing). | Magnesium transporter; Acts as a magnesium transporter. | 0.859 |
SFC38981.1 | SFC95265.1 | SAMN04489722_102338 | SAMN04489722_104139 | GMP synthase (glutamine-hydrolysing). | 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. | 0.494 |
SFC38981.1 | SFD47161.1 | SAMN04489722_102338 | SAMN04489722_11061 | GMP synthase (glutamine-hydrolysing). | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.962 |
SFC38981.1 | guaB | SAMN04489722_102338 | SAMN04489722_10542 | GMP synthase (glutamine-hydrolysing). | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
SFC38981.1 | purA | SAMN04489722_102338 | SAMN04489722_11058 | GMP synthase (glutamine-hydrolysing). | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.945 |
SFC38981.1 | purH | SAMN04489722_102338 | SAMN04489722_108115 | GMP synthase (glutamine-hydrolysing). | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. | 0.925 |
SFC95233.1 | SFC38981.1 | SAMN04489722_104138 | SAMN04489722_102338 | Magnesium transporter; Acts as a magnesium transporter. | GMP synthase (glutamine-hydrolysing). | 0.859 |
SFC95233.1 | SFC95265.1 | SAMN04489722_104138 | SAMN04489722_104139 | Magnesium transporter; Acts as a magnesium transporter. | 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. | 0.778 |
SFC95233.1 | SFC95297.1 | SAMN04489722_104138 | SAMN04489722_104140 | Magnesium transporter; Acts as a magnesium transporter. | AraC-type DNA-binding protein. | 0.491 |
SFC95233.1 | SFD20573.1 | SAMN04489722_104138 | SAMN04489722_10659 | Magnesium transporter; Acts as a magnesium transporter. | cation:H+ antiporter. | 0.416 |
SFC95233.1 | SFD47161.1 | SAMN04489722_104138 | SAMN04489722_11061 | Magnesium transporter; Acts as a magnesium transporter. | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.412 |
SFC95233.1 | guaB | SAMN04489722_104138 | SAMN04489722_10542 | Magnesium transporter; Acts as a magnesium transporter. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.710 |
SFC95233.1 | purA | SAMN04489722_104138 | SAMN04489722_11058 | Magnesium transporter; Acts as a magnesium transporter. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.467 |
SFC95233.1 | purH | SAMN04489722_104138 | SAMN04489722_108115 | Magnesium transporter; Acts as a magnesium transporter. | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. | 0.419 |
SFC95233.1 | rho | SAMN04489722_104138 | SAMN04489722_106106 | Magnesium transporter; Acts as a magnesium transporter. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.416 |
SFC95233.1 | secD | SAMN04489722_104138 | SAMN04489722_11427 | Magnesium transporter; Acts as a magnesium transporter. | SecD/SecF fusion protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.407 |
SFC95265.1 | SFC38981.1 | SAMN04489722_104139 | SAMN04489722_102338 | 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. | GMP synthase (glutamine-hydrolysing). | 0.494 |
SFC95265.1 | SFC95233.1 | SAMN04489722_104139 | SAMN04489722_104138 | 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. | Magnesium transporter; Acts as a magnesium transporter. | 0.778 |
SFC95265.1 | SFC95297.1 | SAMN04489722_104139 | SAMN04489722_104140 | 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. | AraC-type DNA-binding protein. | 0.525 |
SFC95297.1 | SFC95233.1 | SAMN04489722_104140 | SAMN04489722_104138 | AraC-type DNA-binding protein. | Magnesium transporter; Acts as a magnesium transporter. | 0.491 |