SFD31510.1 protein (Algibacter lectus) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

Your Input:

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[Homology]

Score

SFD31510.1

Arginase family enzyme; Belongs to the arginase family. (388 aa)

Predicted Functional Partners:

SFC74376.1

0.889

SFD14065.1

0.872

SFD20448.1

0.871

SFD22384.1

0.861

SFD10296.1

0.857

SFD57115.1

0.857

SFC74683.1

0.855

SFC74337.1

0.854

SFD52943.1

0.853

glsA

0.852

Your Current Organism:

Algibacter lectus

NCBI taxonomy Id: 221126
Other names: A. lectus, Algibacter lectus Nedashkovskaya et al. 2004, Bacteroidetes bacterium KMM 3902, Bacteroidetes bacterium KMM 3914, DSM 15365, JCM 21761, KCTC 12103, KMM 3902

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SFC74337.1	SFC74376.1	SAMN04489722_103325	SAMN04489722_103326	Glutamate synthase (NADH) small subunit.	Glutamate synthase (NADH) large subunit; Belongs to the glutamate synthase family.	0.999
SFC74337.1	SFD10296.1	SAMN04489722_103325	SAMN04489722_105159	Glutamate synthase (NADH) small subunit.	Aspartate aminotransferase.	0.864
SFC74337.1	SFD20448.1	SAMN04489722_103325	SAMN04489722_10654	Glutamate synthase (NADH) small subunit.	Glutamine synthetase.	0.949
SFC74337.1	SFD22384.1	SAMN04489722_103325	SAMN04489722_106121	Glutamate synthase (NADH) small subunit.	Delta-1-pyrroline-5-carboxylate dehydrogenase.	0.865
SFC74337.1	SFD31510.1	SAMN04489722_103325	SAMN04489722_107127	Glutamate synthase (NADH) small subunit.	Arginase family enzyme; Belongs to the arginase family.	0.854
SFC74337.1	SFD57115.1	SAMN04489722_103325	SAMN04489722_11274	Glutamate synthase (NADH) small subunit.	Aspartate aminotransferase.	0.864
SFC74337.1	glsA	SAMN04489722_103325	SAMN04489722_10267	Glutamate synthase (NADH) small subunit.	L-glutaminase; Belongs to the glutaminase family.	0.857
SFC74376.1	SFC74337.1	SAMN04489722_103326	SAMN04489722_103325	Glutamate synthase (NADH) large subunit; Belongs to the glutamate synthase family.	Glutamate synthase (NADH) small subunit.	0.999
SFC74376.1	SFD10296.1	SAMN04489722_103326	SAMN04489722_105159	Glutamate synthase (NADH) large subunit; Belongs to the glutamate synthase family.	Aspartate aminotransferase.	0.943
SFC74376.1	SFD14065.1	SAMN04489722_103326	SAMN04489722_105285	Glutamate synthase (NADH) large subunit; Belongs to the glutamate synthase family.	Argininosuccinate synthase.	0.951
SFC74376.1	SFD20448.1	SAMN04489722_103326	SAMN04489722_10654	Glutamate synthase (NADH) large subunit; Belongs to the glutamate synthase family.	Glutamine synthetase.	0.983
SFC74376.1	SFD22384.1	SAMN04489722_103326	SAMN04489722_106121	Glutamate synthase (NADH) large subunit; Belongs to the glutamate synthase family.	Delta-1-pyrroline-5-carboxylate dehydrogenase.	0.900
SFC74376.1	SFD31510.1	SAMN04489722_103326	SAMN04489722_107127	Glutamate synthase (NADH) large subunit; Belongs to the glutamate synthase family.	Arginase family enzyme; Belongs to the arginase family.	0.889
SFC74376.1	SFD57115.1	SAMN04489722_103326	SAMN04489722_11274	Glutamate synthase (NADH) large subunit; Belongs to the glutamate synthase family.	Aspartate aminotransferase.	0.943
SFC74376.1	glsA	SAMN04489722_103326	SAMN04489722_10267	Glutamate synthase (NADH) large subunit; Belongs to the glutamate synthase family.	L-glutaminase; Belongs to the glutaminase family.	0.941
SFC74683.1	SFD10296.1	SAMN04489722_103335	SAMN04489722_105159	L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.	Aspartate aminotransferase.	0.862
SFC74683.1	SFD14065.1	SAMN04489722_103335	SAMN04489722_105285	L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.	Argininosuccinate synthase.	0.871
SFC74683.1	SFD31510.1	SAMN04489722_103335	SAMN04489722_107127	L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.	Arginase family enzyme; Belongs to the arginase family.	0.855
SFC74683.1	SFD57115.1	SAMN04489722_103335	SAMN04489722_11274	L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.	Aspartate aminotransferase.	0.862
SFD10296.1	SFC74337.1	SAMN04489722_105159	SAMN04489722_103325	Aspartate aminotransferase.	Glutamate synthase (NADH) small subunit.	0.864

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

49

average node degree:

8.91

avg. local clustering coefficient:

0.889

expected number of edges:

16

PPI enrichment p-value:

3.41e-11

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0022900

Electron transport chain

8 of 46

1.63

2.89

2.52e-09

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0010181

FMN binding

5 of 13

1.97

2.96

3.11e-07

GO:0008137

NADH dehydrogenase (ubiquinone) activity

5 of 14

1.94

2.9

3.61e-07

GO:0009055

Electron transfer activity

6 of 27

1.74

2.74

1.05e-07

GO:0051539

4 iron, 4 sulfur cluster binding

8 of 69

1.45

2.3

1.34e-08

GO:0051536

Iron-sulfur cluster binding

9 of 121

1.26

1.82

1.34e-08

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1129

NADH dehydrogenase (ubiquinone) activity, and NuoE domain

6 of 21

1.84

3.15

2.09e-08

CL:1126

Mixed, incl. Electron transport chain, and Alanine, aspartate and glutamate metabolism

9 of 59

1.57

2.99

7.44e-11

CL:1127

Mixed, incl. Electron transport chain, and Citrate cycle (TCA cycle)

8 of 48

1.61

2.93

8.70e-10

CL:1130

NADH dehydrogenase (ubiquinone) activity, and Plasma membrane respirasome

4 of 11

1.95

2.33

1.18e-05

CL:1184

Thiamin diphosphate-binding fold

2 of 5

1.99

0.93

0.0169

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00190

Oxidative phosphorylation

3 of 32

1.36

0.79

0.0167

map01100

Metabolic pathways

10 of 824

0.47

0.36

0.0066

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0677

Repeat

5 of 14

1.94

2.98

2.15e-07

KW-0004

4Fe-4S

7 of 48

1.55

2.42

5.97e-08

KW-1278

Translocase

3 of 16

1.66

1.31

0.0015

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01512

Respiratory-chain NADH dehydrogenase 51 Kd subunit

5 of 7

2.24

3.41

1.27e-07

PF00037

4Fe-4S binding domain

5 of 13

1.97

2.83

6.78e-07

PF10531

SLBB domain

4 of 6

2.21

2.7

4.32e-06

PF01257

Thioredoxin-like [2Fe-2S] ferredoxin

4 of 8

2.09

2.51

7.61e-06

PF13237

4Fe-4S dicluster domain

2 of 3

2.21

1.02

0.0126

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR037225

NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily

6 of 8

2.26

4.12

3.07e-09

IPR011538

NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain

5 of 7

2.24

3.34

1.82e-07

IPR037207

NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily

4 of 4

2.39

2.91

2.49e-06

IPR019575

NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain

4 of 4

2.39

2.91

2.49e-06

IPR001949

NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site

4 of 4

2.39

2.91

2.49e-06

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00928

NADH-ubiquinone oxidoreductase-F iron-sulfur binding region

4 of 4

2.39

3.07

1.14e-06

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