STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiEThiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (217 aa)    
Predicted Functional Partners:
SFD69819.1
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.
 
 0.999
SFD69881.1
Thiamine-phosphate pyrophosphorylase.
  
  0.998
SFD69771.1
Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 0.992
SFD69749.1
Tyrosine lyase ThiH.
 
  
 0.966
SFD69905.1
Hydroxymethylpyrimidine synthase.
 
 
 0.946
SFD69926.1
Sulfur carrier protein ThiS.
 
 
 0.914
thiL
Thiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
 
  
 0.893
rsgA
Ribosome biogenesis GTPase; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
     
 0.856
SFC43551.1
Adenylyltransferase and sulfurtransferase.
 
 
 0.817
SFD69730.1
Predicted thiol-disulfide oxidoreductase YuxK, DCC family.
       0.505
Your Current Organism:
Algibacter lectus
NCBI taxonomy Id: 221126
Other names: A. lectus, Algibacter lectus Nedashkovskaya et al. 2004, Bacteroidetes bacterium KMM 3902, Bacteroidetes bacterium KMM 3914, DSM 15365, JCM 21761, KCTC 12103, KMM 3902
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