node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAU72993.1 | EAU73294.1 | RS9916_25819 | RS9916_27324 | Dihydrolipoamide acetyltransferase; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | Biotin/lipoate A/B protein ligase family; COG0095 Lipoate-protein ligase A. | 0.954 |
EAU72993.1 | EAU73335.1 | RS9916_25819 | RS9916_27529 | Dihydrolipoamide acetyltransferase; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | Probable glutathione reductase (NADPH); COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | 0.998 |
EAU72993.1 | EAU73623.1 | RS9916_25819 | RS9916_28979 | Dihydrolipoamide acetyltransferase; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.999 |
EAU72993.1 | EAU74418.1 | RS9916_25819 | RS9916_32962 | Dihydrolipoamide acetyltransferase; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | 0.999 |
EAU72993.1 | gcvH | RS9916_25819 | RS9916_36747 | Dihydrolipoamide acetyltransferase; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.916 |
EAU72993.1 | lipB | RS9916_25819 | RS9916_25804 | Dihydrolipoamide acetyltransferase; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | Putative lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.790 |
EAU72993.1 | pdhA | RS9916_25819 | RS9916_33012 | Dihydrolipoamide acetyltransferase; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | Pyruvate dehydrogenase (lipoamide); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.999 |
EAU72993.1 | prs | RS9916_25819 | RS9916_31467 | Dihydrolipoamide acetyltransferase; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.981 |
EAU73294.1 | EAU72993.1 | RS9916_27324 | RS9916_25819 | Biotin/lipoate A/B protein ligase family; COG0095 Lipoate-protein ligase A. | Dihydrolipoamide acetyltransferase; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | 0.954 |
EAU73294.1 | EAU73335.1 | RS9916_27324 | RS9916_27529 | Biotin/lipoate A/B protein ligase family; COG0095 Lipoate-protein ligase A. | Probable glutathione reductase (NADPH); COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | 0.876 |
EAU73294.1 | EAU73623.1 | RS9916_27324 | RS9916_28979 | Biotin/lipoate A/B protein ligase family; COG0095 Lipoate-protein ligase A. | Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.907 |
EAU73294.1 | EAU74418.1 | RS9916_27324 | RS9916_32962 | Biotin/lipoate A/B protein ligase family; COG0095 Lipoate-protein ligase A. | COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | 0.876 |
EAU73294.1 | gcvH | RS9916_27324 | RS9916_36747 | Biotin/lipoate A/B protein ligase family; COG0095 Lipoate-protein ligase A. | Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.989 |
EAU73294.1 | lipA | RS9916_27324 | RS9916_31337 | Biotin/lipoate A/B protein ligase family; COG0095 Lipoate-protein ligase A. | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.887 |
EAU73294.1 | lipA-2 | RS9916_27324 | RS9916_39681 | Biotin/lipoate A/B protein ligase family; COG0095 Lipoate-protein ligase A. | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.879 |
EAU73294.1 | lipB | RS9916_27324 | RS9916_25804 | Biotin/lipoate A/B protein ligase family; COG0095 Lipoate-protein ligase A. | Putative lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.868 |
EAU73294.1 | pdhA | RS9916_27324 | RS9916_33012 | Biotin/lipoate A/B protein ligase family; COG0095 Lipoate-protein ligase A. | Pyruvate dehydrogenase (lipoamide); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.903 |
EAU73294.1 | prs | RS9916_27324 | RS9916_31467 | Biotin/lipoate A/B protein ligase family; COG0095 Lipoate-protein ligase A. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.844 |
EAU73335.1 | EAU72993.1 | RS9916_27529 | RS9916_25819 | Probable glutathione reductase (NADPH); COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | Dihydrolipoamide acetyltransferase; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | 0.998 |
EAU73335.1 | EAU73294.1 | RS9916_27529 | RS9916_27324 | Probable glutathione reductase (NADPH); COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | Biotin/lipoate A/B protein ligase family; COG0095 Lipoate-protein ligase A. | 0.876 |