node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAU72958.1 | EAU73776.1 | RS9916_25644 | RS9916_29744 | COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.959 |
EAU72958.1 | EAU74336.1 | RS9916_25644 | RS9916_32552 | COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | Hypothetical protein; COG1231 Monoamine oxidase. | 0.817 |
EAU72958.1 | EAU74701.1 | RS9916_25644 | RS9916_34377 | COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | Putative D-3-phosphoglycerate dehydrogenase (PGDH); COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.828 |
EAU72958.1 | EAU75377.1 | RS9916_25644 | RS9916_37757 | COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | Soluble hydrogenase small subunit; COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase. | 0.649 |
EAU72958.1 | gcvP | RS9916_25644 | RS9916_36742 | COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.943 |
EAU72958.1 | glyA | RS9916_25644 | RS9916_39136 | COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.792 |
EAU73776.1 | EAU72958.1 | RS9916_29744 | RS9916_25644 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | 0.959 |
EAU73776.1 | EAU74701.1 | RS9916_29744 | RS9916_34377 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | Putative D-3-phosphoglycerate dehydrogenase (PGDH); COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.935 |
EAU73776.1 | EAU75360.1 | RS9916_29744 | RS9916_37672 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.908 |
EAU73776.1 | glyA | RS9916_29744 | RS9916_39136 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.615 |
EAU73776.1 | rplB | RS9916_29744 | RS9916_39901 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.988 |
EAU73776.1 | rplF | RS9916_29744 | RS9916_39846 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.987 |
EAU73776.1 | rplP | RS9916_29744 | RS9916_39881 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | 50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | 0.975 |
EAU74336.1 | EAU72958.1 | RS9916_32552 | RS9916_25644 | Hypothetical protein; COG1231 Monoamine oxidase. | COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | 0.817 |
EAU74336.1 | EAU74701.1 | RS9916_32552 | RS9916_34377 | Hypothetical protein; COG1231 Monoamine oxidase. | Putative D-3-phosphoglycerate dehydrogenase (PGDH); COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.919 |
EAU74701.1 | EAU72958.1 | RS9916_34377 | RS9916_25644 | Putative D-3-phosphoglycerate dehydrogenase (PGDH); COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | 0.828 |
EAU74701.1 | EAU73776.1 | RS9916_34377 | RS9916_29744 | Putative D-3-phosphoglycerate dehydrogenase (PGDH); COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.935 |
EAU74701.1 | EAU74336.1 | RS9916_34377 | RS9916_32552 | Putative D-3-phosphoglycerate dehydrogenase (PGDH); COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Hypothetical protein; COG1231 Monoamine oxidase. | 0.919 |
EAU74701.1 | EAU75360.1 | RS9916_34377 | RS9916_37672 | Putative D-3-phosphoglycerate dehydrogenase (PGDH); COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.883 |
EAU74701.1 | EAU75377.1 | RS9916_34377 | RS9916_37757 | Putative D-3-phosphoglycerate dehydrogenase (PGDH); COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Soluble hydrogenase small subunit; COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase. | 0.920 |