STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAQ70281.1Soluble hydrogenase small subunit; COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase. (383 aa)    
Predicted Functional Partners:
gcvP
Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.867
EAQ69306.1
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 
  0.809
EAQ68945.1
COG0516 IMP dehydrogenase/GMP reductase.
   
 0.589
cbiD
CbiD protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
       0.584
EAQ69470.1
Putative D-3-phosphoglycerate dehydrogenase (PGDH); COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 
 0.552
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
       0.550
alaS
Alanyl-tRNA synthetase:DHHA1 domain; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
  
 0.533
purD
Phosphoribosylglycinamide synthetase; COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family.
  
    0.532
EAQ68596.1
Ferredoxin-dependent glutamate synthase, Fd-GOGAT; COG0067 Glutamate synthase domain 1.
  
  
 0.519
gcvT
Putative Glycine cleavage T-protein (aminomethyl transferase); The glycine cleavage system catalyzes the degradation of glycine.
   
 
 0.500
Your Current Organism:
Synechococcus sp. RS9917
NCBI taxonomy Id: 221360
Other names: S. sp. RS9917
Server load: low (16%) [HD]