node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MS1047 | MS1049 | MS1047 | MS1049 | Unknown. | Unknown. | 0.627 |
MS1047 | xthA | MS1047 | MS1048 | Unknown. | XthA protein; Exonuclease III. | 0.661 |
MS1049 | MS1047 | MS1049 | MS1047 | Unknown. | Unknown. | 0.627 |
MS1049 | xthA | MS1049 | MS1048 | Unknown. | XthA protein; Exonuclease III. | 0.757 |
cDC9 | dnaN | MS0939 | MS0486 | CDC9 protein; ATP-dependent DNA ligase. | DnaN protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well [...] | 0.992 |
cDC9 | holB | MS0939 | MS0570 | CDC9 protein; ATP-dependent DNA ligase. | HolB protein; ATPase involved in DNA replication. | 0.832 |
cDC9 | polA | MS0939 | MS0225 | CDC9 protein; ATP-dependent DNA ligase. | PolA protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.873 |
cDC9 | xthA | MS0939 | MS1048 | CDC9 protein; ATP-dependent DNA ligase. | XthA protein; Exonuclease III. | 0.997 |
dnaN | cDC9 | MS0486 | MS0939 | DnaN protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well [...] | CDC9 protein; ATP-dependent DNA ligase. | 0.992 |
dnaN | holB | MS0486 | MS0570 | DnaN protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well [...] | HolB protein; ATPase involved in DNA replication. | 0.999 |
dnaN | mutY | MS0486 | MS0317 | DnaN protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well [...] | MutY protein; Adenine glycosylase active on G-A mispairs. | 0.479 |
dnaN | polA | MS0486 | MS0225 | DnaN protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well [...] | PolA protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.998 |
dnaN | ung | MS0486 | MS0373 | DnaN protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well [...] | Ung protein; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.607 |
dnaN | xthA | MS0486 | MS1048 | DnaN protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well [...] | XthA protein; Exonuclease III. | 0.873 |
hfq | polA | MS1518 | MS0225 | Hfq protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | PolA protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.475 |
hfq | xthA | MS1518 | MS1048 | Hfq protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | XthA protein; Exonuclease III. | 0.718 |
holB | cDC9 | MS0570 | MS0939 | HolB protein; ATPase involved in DNA replication. | CDC9 protein; ATP-dependent DNA ligase. | 0.832 |
holB | dnaN | MS0570 | MS0486 | HolB protein; ATPase involved in DNA replication. | DnaN protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well [...] | 0.999 |
holB | polA | MS0570 | MS0225 | HolB protein; ATPase involved in DNA replication. | PolA protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.922 |
holB | xthA | MS0570 | MS1048 | HolB protein; ATPase involved in DNA replication. | XthA protein; Exonuclease III. | 0.648 |