STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
miaB-2MiaB protein; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (448 aa)    
Predicted Functional Partners:
MS2246
Unknown.
     
 0.640
thiI
ThiI protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
  
 0.479
pspE-3
PspE protein; Rhodanese-related sulfurtransferases.
     
 0.454
rlmN
Unknown; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.
 
  
 0.438
MS0246
Unknown; Belongs to the RNase T2 family.
 
     0.428
lepB
LepB protein; Signal peptidase I; Belongs to the peptidase S26 family.
  
    0.406
lepB-2
LepB protein; Signal peptidase I; Belongs to the peptidase S26 family.
  
    0.406
glnS-2
GlnS protein; Glutamyl- and glutaminyl-tRNA synthetases.
   
  
 0.400
Your Current Organism:
Mannheimia succiniciproducens
NCBI taxonomy Id: 221988
Other names: Mannheimia succiniciproducens MBEL55E, Mannheimia succiniciproducens str. MBEL55E, [. succiniciproducens MBEL55E, [Mannheimia] succiniciproducens MBEL55E
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