STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hyaBHyaB protein; Ni, Fe-hydrogenase I large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (569 aa)    
Predicted Functional Partners:
hyaA
HyaA protein; Ni, Fe-hydrogenase I small subunit.
 
 0.999
hyaD
HyaD protein; Ni, Fe-hydrogenase maturation factor.
 
 
 0.974
MS2359
Unknown.
 
  
 0.956
MS2362
Unknown.
 
  
 0.954
hypC
HypC protein; Hydrogenase maturation factor.
 
 
 0.919
hybF
Zn finger protein HypA/HybF (possibly regulating hydrogenase expression).
 
 
 0.906
hypD
HypD protein; Hydrogenase maturation factor; Belongs to the HypD family.
 
 
 0.799
hypB
HypB protein; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase.
 
  
 0.791
hypE
HypE protein; Hydrogenase maturation factor.
 
   
 0.742
hypF
HypF protein; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
 
 
 0.707
Your Current Organism:
Mannheimia succiniciproducens
NCBI taxonomy Id: 221988
Other names: Mannheimia succiniciproducens MBEL55E, Mannheimia succiniciproducens str. MBEL55E, [. succiniciproducens MBEL55E, [Mannheimia] succiniciproducens MBEL55E
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