Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
panDAspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (121 aa)    
Predicted Functional Partners:
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
 
 0.995
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
  
  
 0.941
ANV97798.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.868
ANV97354.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MurCDEF family. MurE subfamily.
     
 0.824
ANV97350.1
Geranyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family.
       0.822
ANV97351.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.822
ANV97352.1
Nucleoid-associated protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
       0.822
ANV97675.1
Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.821
ANV97355.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.820
ANV97356.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.820
Your Current Organism:
Helicobacter sp. MIT016242
NCBI taxonomy Id: 222136
Other names: H. sp. MIT 01-6242, Helicobacter sp. MIT 01-6242
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