STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOS93258.1Nitroreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)    
Predicted Functional Partners:
fbiA
2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
 
   
 0.785
AOS90265.1
LLM class F420-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.764
AOS90620.1
LLM class F420-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.762
APD83820.1
LLM class F420-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.738
AOS93585.1
LLM class F420-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.738
fbiB
Coenzyme F420-0:L-glutamate ligase; Bifunctional enzyme that catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2- dependent reduction of dehydro-F420-0 to form F420-0. In the N-terminal section; belongs to the CofE family.
 
   
 0.736
AOS94136.1
F420-dependent methylene-tetrahydromethanopterin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.733
fgd
Glucose-6-phosphate dehydrogenase (coenzyme-F420); Catalyzes the coenzyme F420-dependent oxidation of glucose 6- phosphate (G6P) to 6-phosphogluconolactone. Appears to have a role in resistance to oxidative stress, via its consumption of G6P that serves as a source of reducing power to combat oxidative stress in mycobacteria.
  
   
 0.716
fbiD
2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
 
   
 0.693
AOS90491.1
LLM class F420-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.677
Your Current Organism:
Mycobacterium chimaera
NCBI taxonomy Id: 222805
Other names: CCUG 50989, CIP 107892, DSM 44623, JCM 14737, M. chimaera, Mycobacterium chimaera Tortoli et al. 2004, NCTC 13781, personal::FI-01069, strain FI-01069
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