STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NSE_0846Putative membrane protein; Identified by match to protein family HMM PF07690. (399 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; Identified by similarity to SP:O34996; match to protein family HMM PF00476; match to protein family HMM PF01367; match to protein family HMM PF02739; match to protein family HMM TIGR00593.
 
   
 0.662
NSE_0005
Iron-binding protein; Identified by similarity to GB:AAD03802.1; match to protein family HMM PF01547.
  
  
 0.641
pheT
Putative phenylalanyl-tRNA synthetase, beta subunit; Identified by similarity to SP:P07395; match to protein family HMM PF01588; match to protein family HMM PF03483; match to protein family HMM PF03484; match to protein family HMM TIGR00472; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
     
 0.501
NSE_0198
Putative transporter; Identified by similarity to GB:AAL95344.1; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
 
   
 0.491
NSE_0845
Branched-chain amino acid transporter; Component of the transport system for branched-chain amino acids.
     
 0.473
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
      0.434
NSE_0844
Identified by match to protein family HMM PF00814.
       0.429
Your Current Organism:
Neorickettsia sennetsu
NCBI taxonomy Id: 222891
Other names: N. sennetsu str. Miyayama, Neorickettsia sennetsu Miyayama, Neorickettsia sennetsu str. Miyayama
Server load: low (16%) [HD]