node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NSE_0190 | NSE_0230 | NSE_0190 | NSE_0230 | Conserved hypothetical protein; Identified by similarity to GB:AAR38359.1; Belongs to the DnaA family. | Identified by match to protein family HMM PF01381. | 0.497 |
NSE_0190 | NSE_0503 | NSE_0190 | NSE_0503 | Conserved hypothetical protein; Identified by similarity to GB:AAR38359.1; Belongs to the DnaA family. | Conserved hypothetical protein; Identified by similarity to SP:Q9A3C9; Belongs to the bacterial ribosomal protein bL31 family. | 0.733 |
NSE_0190 | ribE-2 | NSE_0190 | NSE_0853 | Conserved hypothetical protein; Identified by similarity to GB:AAR38359.1; Belongs to the DnaA family. | Riboflavin synthase, alpha subunit; Identified by similarity to SP:P16440; match to protein family HMM PF00677; match to protein family HMM TIGR00187. | 0.546 |
NSE_0230 | NSE_0190 | NSE_0230 | NSE_0190 | Identified by match to protein family HMM PF01381. | Conserved hypothetical protein; Identified by similarity to GB:AAR38359.1; Belongs to the DnaA family. | 0.497 |
NSE_0230 | ribA | NSE_0230 | NSE_0745 | Identified by match to protein family HMM PF01381. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.495 |
NSE_0230 | ribB | NSE_0230 | NSE_0649 | Identified by match to protein family HMM PF01381. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Identified by match to protein family HMM PF00926; match to protein family HMM TIGR00506. | 0.497 |
NSE_0230 | ribD | NSE_0230 | NSE_0499 | Identified by match to protein family HMM PF01381. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.495 |
NSE_0230 | ribE-2 | NSE_0230 | NSE_0853 | Identified by match to protein family HMM PF01381. | Riboflavin synthase, alpha subunit; Identified by similarity to SP:P16440; match to protein family HMM PF00677; match to protein family HMM TIGR00187. | 0.495 |
NSE_0503 | NSE_0190 | NSE_0503 | NSE_0190 | Conserved hypothetical protein; Identified by similarity to SP:Q9A3C9; Belongs to the bacterial ribosomal protein bL31 family. | Conserved hypothetical protein; Identified by similarity to GB:AAR38359.1; Belongs to the DnaA family. | 0.733 |
NSE_0503 | ribE-2 | NSE_0503 | NSE_0853 | Conserved hypothetical protein; Identified by similarity to SP:Q9A3C9; Belongs to the bacterial ribosomal protein bL31 family. | Riboflavin synthase, alpha subunit; Identified by similarity to SP:P16440; match to protein family HMM PF00677; match to protein family HMM TIGR00187. | 0.667 |
lgt | ribE-2 | NSE_0854 | NSE_0853 | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Riboflavin synthase, alpha subunit; Identified by similarity to SP:P16440; match to protein family HMM PF00677; match to protein family HMM TIGR00187. | 0.547 |
pheS | ribE-2 | NSE_0216 | NSE_0853 | phenylalanyl-tRNA synthetase, alpha subunit; Identified by similarity to SP:P08312; match to protein family HMM PF01409; match to protein family HMM TIGR00468; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | Riboflavin synthase, alpha subunit; Identified by similarity to SP:P16440; match to protein family HMM PF00677; match to protein family HMM TIGR00187. | 0.648 |
ribA | NSE_0230 | NSE_0745 | NSE_0230 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | Identified by match to protein family HMM PF01381. | 0.495 |
ribA | ribB | NSE_0745 | NSE_0649 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Identified by match to protein family HMM PF00926; match to protein family HMM TIGR00506. | 0.976 |
ribA | ribD | NSE_0745 | NSE_0499 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
ribA | ribE-1 | NSE_0745 | NSE_0401 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.983 |
ribA | ribE-2 | NSE_0745 | NSE_0853 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | Riboflavin synthase, alpha subunit; Identified by similarity to SP:P16440; match to protein family HMM PF00677; match to protein family HMM TIGR00187. | 0.998 |
ribA | ribF | NSE_0745 | NSE_0040 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | Riboflavin biosynthesis protein RibF; Identified by similarity to SP:P54575; match to protein family HMM PF01687; match to protein family HMM PF06574; match to protein family HMM TIGR00083; Belongs to the ribF family. | 0.497 |
ribB | NSE_0230 | NSE_0649 | NSE_0230 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Identified by match to protein family HMM PF00926; match to protein family HMM TIGR00506. | Identified by match to protein family HMM PF01381. | 0.497 |
ribB | ribA | NSE_0649 | NSE_0745 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Identified by match to protein family HMM PF00926; match to protein family HMM TIGR00506. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.976 |