node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NSE_0385 | NSE_0940 | NSE_0385 | NSE_0940 | Putative porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | AraM domain protein; Identified by similarity to SP:P94527. | 0.448 |
NSE_0385 | glyA | NSE_0385 | NSE_0218 | Putative porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.525 |
NSE_0385 | purD | NSE_0385 | NSE_0924 | Putative porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Phosphoribosylamine--glycine ligase; Identified by similarity to SP:P15640; match to protein family HMM PF01071; match to protein family HMM PF02842; match to protein family HMM PF02843; match to protein family HMM PF02844; match to protein family HMM TIGR00877. | 0.474 |
NSE_0385 | ubiA | NSE_0385 | NSE_0806 | Putative porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.527 |
NSE_0407 | NSE_0420 | NSE_0407 | NSE_0420 | Identified by similarity to GB:AAG30826.1; match to protein family HMM PF01553. | Malate dehydrogenase; Identified by similarity to SP:O30808; match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949. | 0.417 |
NSE_0407 | NSE_0940 | NSE_0407 | NSE_0940 | Identified by similarity to GB:AAG30826.1; match to protein family HMM PF01553. | AraM domain protein; Identified by similarity to SP:P94527. | 0.800 |
NSE_0407 | gpsA | NSE_0407 | NSE_0228 | Identified by similarity to GB:AAG30826.1; match to protein family HMM PF01553. | Glycerol-3-phosphate dehydrogenase (NAD(P)+); Identified by similarity to SP:P46919; match to protein family HMM PF01210; match to protein family HMM PF07479; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.901 |
NSE_0420 | NSE_0407 | NSE_0420 | NSE_0407 | Malate dehydrogenase; Identified by similarity to SP:O30808; match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949. | Identified by similarity to GB:AAG30826.1; match to protein family HMM PF01553. | 0.417 |
NSE_0420 | NSE_0940 | NSE_0420 | NSE_0940 | Malate dehydrogenase; Identified by similarity to SP:O30808; match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949. | AraM domain protein; Identified by similarity to SP:P94527. | 0.518 |
NSE_0420 | glyA | NSE_0420 | NSE_0218 | Malate dehydrogenase; Identified by similarity to SP:O30808; match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.670 |
NSE_0420 | gpsA | NSE_0420 | NSE_0228 | Malate dehydrogenase; Identified by similarity to SP:O30808; match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949. | Glycerol-3-phosphate dehydrogenase (NAD(P)+); Identified by similarity to SP:P46919; match to protein family HMM PF01210; match to protein family HMM PF07479; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.524 |
NSE_0939 | NSE_0940 | NSE_0939 | NSE_0940 | Type I secretion membrane fusion protein, HlyD family; Identified by match to protein family HMM PF00529; match to protein family HMM TIGR01843. | AraM domain protein; Identified by similarity to SP:P94527. | 0.486 |
NSE_0939 | NSE_0941 | NSE_0939 | NSE_0941 | Type I secretion membrane fusion protein, HlyD family; Identified by match to protein family HMM PF00529; match to protein family HMM TIGR01843. | Conserved hypothetical protein; Identified by similarity to PIR:D97574; match to protein family HMM PF03937. | 0.486 |
NSE_0940 | NSE_0385 | NSE_0940 | NSE_0385 | AraM domain protein; Identified by similarity to SP:P94527. | Putative porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.448 |
NSE_0940 | NSE_0407 | NSE_0940 | NSE_0407 | AraM domain protein; Identified by similarity to SP:P94527. | Identified by similarity to GB:AAG30826.1; match to protein family HMM PF01553. | 0.800 |
NSE_0940 | NSE_0420 | NSE_0940 | NSE_0420 | AraM domain protein; Identified by similarity to SP:P94527. | Malate dehydrogenase; Identified by similarity to SP:O30808; match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949. | 0.518 |
NSE_0940 | NSE_0939 | NSE_0940 | NSE_0939 | AraM domain protein; Identified by similarity to SP:P94527. | Type I secretion membrane fusion protein, HlyD family; Identified by match to protein family HMM PF00529; match to protein family HMM TIGR01843. | 0.486 |
NSE_0940 | NSE_0941 | NSE_0940 | NSE_0941 | AraM domain protein; Identified by similarity to SP:P94527. | Conserved hypothetical protein; Identified by similarity to PIR:D97574; match to protein family HMM PF03937. | 0.773 |
NSE_0940 | ffh | NSE_0940 | NSE_0540 | AraM domain protein; Identified by similarity to SP:P94527. | Signal recognition particle protein; Identified by similarity to SP:P37105; match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM PF02978. | 0.465 |
NSE_0940 | glyA | NSE_0940 | NSE_0218 | AraM domain protein; Identified by similarity to SP:P94527. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.461 |