node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NSE_0366 | NSE_0746 | NSE_0366 | NSE_0746 | Sensor histidine kinase/response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518. | Putative pyruvate dehydrogenase complex, E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.882 |
NSE_0366 | gltA | NSE_0366 | NSE_0730 | Sensor histidine kinase/response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518. | Citrate synthase; Identified by similarity to SP:P51042; match to protein family HMM PF00285; Belongs to the citrate synthase family. | 0.561 |
NSE_0366 | lpdA-1 | NSE_0366 | NSE_0463 | Sensor histidine kinase/response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518. | Dihydrolipoamide dehydrogenase; Identified by similarity to SP:P54533; match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF01266; match to protein family HMM PF02852; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR01350. | 0.803 |
NSE_0366 | lpdA-2 | NSE_0366 | NSE_0671 | Sensor histidine kinase/response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518. | Dihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF01266; match to protein family HMM PF02852; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR01350. | 0.803 |
NSE_0366 | pdhA | NSE_0366 | NSE_0802 | Sensor histidine kinase/response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518. | Pyruvate dehydrogenase complex, E1 component, pyruvate dehydrogenase alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.620 |
NSE_0366 | pdhC | NSE_0366 | NSE_0953 | Sensor histidine kinase/response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518. | Pyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.865 |
NSE_0366 | prs | NSE_0366 | NSE_0816 | Sensor histidine kinase/response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518. | Ribose-phosphate pyrophosphokinase; Identified by similarity to SP:P08330; match to protein family HMM PF00156; match to protein family HMM TIGR01251. | 0.880 |
NSE_0366 | sucC | NSE_0366 | NSE_0251 | Sensor histidine kinase/response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518. | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.544 |
NSE_0746 | NSE_0366 | NSE_0746 | NSE_0366 | Putative pyruvate dehydrogenase complex, E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Sensor histidine kinase/response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518. | 0.882 |
NSE_0746 | gltA | NSE_0746 | NSE_0730 | Putative pyruvate dehydrogenase complex, E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Citrate synthase; Identified by similarity to SP:P51042; match to protein family HMM PF00285; Belongs to the citrate synthase family. | 0.677 |
NSE_0746 | lpdA-1 | NSE_0746 | NSE_0463 | Putative pyruvate dehydrogenase complex, E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Dihydrolipoamide dehydrogenase; Identified by similarity to SP:P54533; match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF01266; match to protein family HMM PF02852; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR01350. | 0.998 |
NSE_0746 | lpdA-2 | NSE_0746 | NSE_0671 | Putative pyruvate dehydrogenase complex, E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Dihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF01266; match to protein family HMM PF02852; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR01350. | 0.998 |
NSE_0746 | pdhA | NSE_0746 | NSE_0802 | Putative pyruvate dehydrogenase complex, E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Pyruvate dehydrogenase complex, E1 component, pyruvate dehydrogenase alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.999 |
NSE_0746 | pdhC | NSE_0746 | NSE_0953 | Putative pyruvate dehydrogenase complex, E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Pyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.999 |
NSE_0746 | prs | NSE_0746 | NSE_0816 | Putative pyruvate dehydrogenase complex, E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Ribose-phosphate pyrophosphokinase; Identified by similarity to SP:P08330; match to protein family HMM PF00156; match to protein family HMM TIGR01251. | 0.997 |
NSE_0746 | sucA | NSE_0746 | NSE_0578 | Putative pyruvate dehydrogenase complex, E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 2-oxoglutarate dehydrogenase, E1 component; Identified by similarity to SP:P07015; match to protein family HMM PF00676; match to protein family HMM PF02779; match to protein family HMM TIGR00239. | 0.965 |
NSE_0746 | sucC | NSE_0746 | NSE_0251 | Putative pyruvate dehydrogenase complex, E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.569 |
NSE_0746 | sucD | NSE_0746 | NSE_0250 | Putative pyruvate dehydrogenase complex, E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.608 |
gltA | NSE_0366 | NSE_0730 | NSE_0366 | Citrate synthase; Identified by similarity to SP:P51042; match to protein family HMM PF00285; Belongs to the citrate synthase family. | Sensor histidine kinase/response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518. | 0.561 |
gltA | NSE_0746 | NSE_0730 | NSE_0746 | Citrate synthase; Identified by similarity to SP:P51042; match to protein family HMM PF00285; Belongs to the citrate synthase family. | Putative pyruvate dehydrogenase complex, E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.677 |