STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ELS17_03550Unannotated protein; Involved in regulation of DNA replication. (428 aa)    
Predicted Functional Partners:
ELS17_06430
Unannotated protein.
  
 0.943
priL
Unannotated protein; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
  
 0.812
ELS17_12545
Unannotated protein.
  
 0.767
priS
Unannotated protein; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May al [...]
  
 
 0.719
ELS17_16310
Unannotated protein.
  
     0.685
dnaG
Unannotated protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
  
   
 0.663
GCA_000731985_02240
Unannotated protein.
 
   
 0.663
eif5a
Unannotated protein; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
  
     0.649
ELS17_13845
Unannotated protein; Involved in DNA damage repair.
  
     0.634
ELS17_08720
Unannotated protein.
  
     0.634
Your Current Organism:
Natrinema altunense
NCBI taxonomy Id: 222984
Other names: AS 1.3731, JCM 12890, N. altunense, Natrinema aibiensis, Natrinema ajinwuensis, Natrinema altuensis, Natrinema altunense Xu et al. 2005, strain AJ2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.