STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ELS17_13725Unannotated protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (494 aa)    
Predicted Functional Partners:
leuD
Unannotated protein.
 
 
 0.987
leuC
Unannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 
 0.985
ELS17_13575
Unannotated protein.
 
 0.947
ilvN
Unannotated protein.
 
 
 0.941
ELS17_12795
Unannotated protein.
    
 0.929
ilvD
Unannotated protein; Belongs to the IlvD/Edd family.
 
 
 0.926
ilvE
Unannotated protein; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
 
 0.898
ELS17_18285
Unannotated protein; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
 
 0.898
ilvC
Unannotated protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
  
 0.879
ilvB
Unannotated protein.
 
 
 0.878
Your Current Organism:
Natrinema altunense
NCBI taxonomy Id: 222984
Other names: AS 1.3731, JCM 12890, N. altunense, Natrinema aibiensis, Natrinema ajinwuensis, Natrinema altuensis, Natrinema altunense Xu et al. 2005, strain AJ2
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