node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AS25_00235 | AS25_09235 | AS25_00235 | AS25_09235 | Fe-S cluster assembly protein HesB; Derived by automated computational analysis using gene prediction method: Protein Homology. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. Belongs to the FPG family. | 0.723 |
AS25_00235 | AS25_13320 | AS25_00235 | AS25_13320 | Fe-S cluster assembly protein HesB; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.434 |
AS25_00235 | polA | AS25_00235 | AS25_04470 | Fe-S cluster assembly protein HesB; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.443 |
AS25_00235 | recA | AS25_00235 | AS25_05990 | Fe-S cluster assembly protein HesB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.429 |
AS25_00235 | recO | AS25_00235 | AS25_03925 | Fe-S cluster assembly protein HesB; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA recombination protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.710 |
AS25_01560 | polA | AS25_01560 | AS25_04470 | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.447 |
AS25_01560 | recO | AS25_01560 | AS25_03925 | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA recombination protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.615 |
AS25_01560 | recR | AS25_01560 | AS25_01745 | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | Recombinase RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.530 |
AS25_03930 | era | AS25_03930 | AS25_03910 | UDP pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.685 |
AS25_03930 | leuA | AS25_03930 | AS25_03920 | UDP pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.574 |
AS25_03930 | polA | AS25_03930 | AS25_04470 | UDP pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.405 |
AS25_03930 | recO | AS25_03930 | AS25_03925 | UDP pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | DNA recombination protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.817 |
AS25_09235 | AS25_00235 | AS25_09235 | AS25_00235 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. Belongs to the FPG family. | Fe-S cluster assembly protein HesB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.723 |
AS25_09235 | AS25_13320 | AS25_09235 | AS25_13320 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. Belongs to the FPG family. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.554 |
AS25_09235 | polA | AS25_09235 | AS25_04470 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. Belongs to the FPG family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.908 |
AS25_09235 | recA | AS25_09235 | AS25_05990 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. Belongs to the FPG family. | Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.737 |
AS25_09235 | recO | AS25_09235 | AS25_03925 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. Belongs to the FPG family. | DNA recombination protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.615 |
AS25_13320 | AS25_00235 | AS25_13320 | AS25_00235 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Fe-S cluster assembly protein HesB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.434 |
AS25_13320 | AS25_09235 | AS25_13320 | AS25_09235 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. Belongs to the FPG family. | 0.554 |
AS25_13320 | polA | AS25_13320 | AS25_04470 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.576 |