Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AS25_09490Phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)    
Predicted Functional Partners:
AS25_09495
Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
     
 0.780
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
       0.780
AS25_01305
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.762
AS25_11070
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.709
AS25_05265
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.696
AS25_02165
Subtilisin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S8 family.
  
     0.695
AS25_09485
DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.686
AS25_09110
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.676
AS25_13490
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.643
AS25_04720
Phosphopantetheinyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the P-Pant transferase superfamily.
  
     0.616
Your Current Organism:
Kocuria marina
NCBI taxonomy Id: 223184
Other names: CCUG 51442, JCM 13363, KCTC 9943, KMM 3905, Kocuria marina Kim et al. 2004, Kocuria sp. KMM 3905
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