Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nucSHypothetical protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family. (231 aa)    
Predicted Functional Partners:
whiB-2
WhiB family transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.722
AS25_09540
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.704
AS25_02835
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.657
whiB
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.656
AS25_09555
Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.642
AS25_05310
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 
 0.636
AS25_11685
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.625
AS25_11100
Fructose-2,6-bisphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.581
AS25_03310
dUTPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.572
AS25_04340
Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
  
     0.567
Your Current Organism:
Kocuria marina
NCBI taxonomy Id: 223184
Other names: CCUG 51442, JCM 13363, KCTC 9943, KMM 3905, Kocuria marina Kim et al. 2004, Kocuria sp. KMM 3905
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