Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ntrCNitrogen regulation protein NR(I); Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (478 aa)    
Predicted Functional Partners:
ntrB
Nitrogen regulation protein NtrB.
 0.999
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.912
AAO53898.1
Hypothetical protein; Identified by Glimmer2; putative.
       0.773
fleN
Flagellar synthesis regulator FleN; See PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF02374.
  
 
 0.677
glnK
Nitrogen regulatory protein P-II; Similar to GP:2735324; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to GP:2735324, identified by sequence similarity, putative; Belongs to the P(II) protein family.
   
 
 0.651
aroH
Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate.
       0.643
AAO53980.1
Conserved hypothetical protein; Identified by Glimmer2; putative.
     
 0.636
phoR
Phosphate regulon sensor protein phoR.
 
 
 0.596
thiI
Thiamin biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
       0.562
AAO58442.1
Response regulator/sensory box/GGDEF domain/EAL domain protein; See PMID:20190049 for expression data.
  
 
 0.558
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
Server load: low (20%) [HD]