Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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hopF2Type III effector HopF2; This gene has an isoleucine start. Previously known as HolPtoAD (PMID11872842; Guttman et al, 2002) and HopPtoF (PMID11854524; Fouts et al, 2002); see PMID:20190049 for expression data; similar to GP:7677395; identified by sequence similarity; putative. (204 aa)    
Predicted Functional Partners:
hopAB2
Type III effector HopAB2; Effector protein involved in gene-for-gene resistance in tomato plants. It is recognized by the host Pto resistance protein and elicits Pto and Prf-dependent hypersensitive response (HR) and programmed cell death (PCD), resulting in host immunity. In susceptible plants, acts as a virulence factor by suppressing PCD and HR-based plant immunity. This function requires its E3 ubiquitin ligase activity probably by recruiting E2 enzymes and transferring ubiquitin molecules to cellular proteins involved in regulation of PCD and targeting them for degradation. Also, [...]
      
 0.806
hopAI1
Type III effector HopAI1; Previously known as HolPtoAI (PMID12615215; Greenberg and Vinatzer, 2003); similar to SP:P21456, GB:M33318, GB:X13897, GB:X13929, GB:X06401, GB:X13930, SP:P11509, SP:P20853, PID:180987, PID:29547, PID:30332, and PID:825700; identified by sequence similarity; putative.
      
 0.802
hopU1
Type III effector HopU1; Previously known as HopPtoS2 (PMID12032338; Petnicki-Ocwieja et al, 2002).
     
 0.799
shcF
Type III chaperone protein ShcF; See PMID:20190049 for expression data.
     
 0.760
fliC
Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
      
 0.630
hopM1
Type III effector HopM1; Involved in the suppression of basal resistance and promotion of disease symptoms in plants. Mediates the ubiquitination and degradation, via the host proteasome, of a low-abundance immunity- associated protein in Arabidopsis thaliana. May be involved in the inhibition of a host vesicle trafficking pathway.
      
 0.625
hopAF1
Type III effector HopAF1; Previously known as HolPtoN (PMID11872842; Guttman et al, 2002) and HopPtoJ (PMID12032338; Petnicki-Ocwieja et al, 2002); see PMID:20190049 for expression data.
      
 0.523
hopAO1
Type III effector HopAO1; Effector showing tyrosine-phosphatase activity required for host defense suppression. Functions inside plant cells causing suppression of HR (hypersensitive response), PR1 gene expression and oxidative burst probably by interfering with a MAPK (mitogen-activated protein kinase) pathway. MAPK cascades are known to activate defense- related transcription factors. Inhibits plant pattern-recognition receptors (PRRs) activation.
      
 0.523
hopB1
Type III effector HopB1; Also known as EEL ORF1 (PMID10781092; Alfano et al, 2000) and HopPtoB (PMID11872842; Guttman et al, 2002); see PMID:20190049 for expression data; similar to GP:8037777; identified by sequence similarity; putative.
      
 0.497
hopC1
Type III effector HopC1; Previously known as HopPtoC (PMID12032338; Petnicki-Ocwieja et al, 2002); see PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01586.
      
 0.491
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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