| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| apaG | apaH | PSPTO_0550 | PSPTO_0549 | apaG protein. | Bis(5'-nucleosyl)-tetraphosphatase, symmetrical; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 0.965 |
| apaG | ksgA | PSPTO_0550 | PSPTO_0551 | apaG protein. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.935 |
| apaG | lptD | PSPTO_0550 | PSPTO_0554 | apaG protein. | Organic solvent tolerance protein, putative; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | 0.756 |
| apaG | pdxA | PSPTO_0550 | PSPTO_0552 | apaG protein. | Pyridoxal phosphate biosynthetic protein PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | 0.837 |
| apaG | surA | PSPTO_0550 | PSPTO_0553 | apaG protein. | Peptidyl-prolyl cis-trans isomerase SurA; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. | 0.839 |
| apaH | apaG | PSPTO_0549 | PSPTO_0550 | Bis(5'-nucleosyl)-tetraphosphatase, symmetrical; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | apaG protein. | 0.965 |
| apaH | ksgA | PSPTO_0549 | PSPTO_0551 | Bis(5'-nucleosyl)-tetraphosphatase, symmetrical; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.864 |
| apaH | lptD | PSPTO_0549 | PSPTO_0554 | Bis(5'-nucleosyl)-tetraphosphatase, symmetrical; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Organic solvent tolerance protein, putative; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | 0.848 |
| apaH | pdxA | PSPTO_0549 | PSPTO_0552 | Bis(5'-nucleosyl)-tetraphosphatase, symmetrical; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Pyridoxal phosphate biosynthetic protein PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | 0.830 |
| apaH | surA | PSPTO_0549 | PSPTO_0553 | Bis(5'-nucleosyl)-tetraphosphatase, symmetrical; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Peptidyl-prolyl cis-trans isomerase SurA; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. | 0.873 |
| ksgA | apaG | PSPTO_0551 | PSPTO_0550 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | apaG protein. | 0.935 |
| ksgA | apaH | PSPTO_0551 | PSPTO_0549 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Bis(5'-nucleosyl)-tetraphosphatase, symmetrical; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 0.864 |
| ksgA | lptD | PSPTO_0551 | PSPTO_0554 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Organic solvent tolerance protein, putative; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | 0.906 |
| ksgA | pdxA | PSPTO_0551 | PSPTO_0552 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Pyridoxal phosphate biosynthetic protein PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | 0.939 |
| ksgA | rimP | PSPTO_0551 | PSPTO_4492 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Conserved protein of unknown function; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | 0.835 |
| ksgA | rpsE | PSPTO_0551 | PSPTO_0643 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. | 0.908 |
| ksgA | rpsI | PSPTO_0551 | PSPTO_4425 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Ribosomal protein S9; See PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF00380; Belongs to the universal ribosomal protein uS9 family. | 0.846 |
| ksgA | rpsK | PSPTO_0551 | PSPTO_0649 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.847 |
| ksgA | rpsL | PSPTO_0551 | PSPTO_0621 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | 0.884 |
| ksgA | surA | PSPTO_0551 | PSPTO_0553 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Peptidyl-prolyl cis-trans isomerase SurA; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. | 0.945 |