| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AAO53767.1 | ribD | PSPTO_0221 | PSPTO_0690 | HAD-superfamily hydrolase; See PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01691. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.919 |
| AAO53767.1 | ribE | PSPTO_0221 | PSPTO_0691 | HAD-superfamily hydrolase; See PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01691. | Riboflavin synthase, alpha subunit; See PMID:20190049 for expression data. | 0.901 |
| AAO53767.1 | ribF | PSPTO_0221 | PSPTO_0805 | HAD-superfamily hydrolase; See PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01691. | Riboflavin biosynthesis protein RibF; See PMID:20190049 for expression data; Belongs to the ribF family. | 0.919 |
| AAO53767.1 | ribH-1 | PSPTO_0221 | PSPTO_0693 | HAD-superfamily hydrolase; See PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01691. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.903 |
| AAO53767.1 | ribH-2 | PSPTO_0221 | PSPTO_1839 | HAD-superfamily hydrolase; See PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01691. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.903 |
| AAO54375.1 | ribA | PSPTO_0835 | PSPTO_0696 | ribD C-terminal domain protein; See PMID:20190049 for expression data; similar to GB:S69136, GB:S69198, GB:M28594, and PID:292763; identified by sequence similarity; putative. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.982 |
| AAO54375.1 | ribBA-1 | PSPTO_0835 | PSPTO_0692 | ribD C-terminal domain protein; See PMID:20190049 for expression data; similar to GB:S69136, GB:S69198, GB:M28594, and PID:292763; identified by sequence similarity; putative. | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.994 |
| AAO54375.1 | ribBA-2 | PSPTO_0835 | PSPTO_2668 | ribD C-terminal domain protein; See PMID:20190049 for expression data; similar to GB:S69136, GB:S69198, GB:M28594, and PID:292763; identified by sequence similarity; putative. | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | 0.994 |
| AAO54375.1 | ribD | PSPTO_0835 | PSPTO_0690 | ribD C-terminal domain protein; See PMID:20190049 for expression data; similar to GB:S69136, GB:S69198, GB:M28594, and PID:292763; identified by sequence similarity; putative. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.933 |
| AAO54375.1 | ribE | PSPTO_0835 | PSPTO_0691 | ribD C-terminal domain protein; See PMID:20190049 for expression data; similar to GB:S69136, GB:S69198, GB:M28594, and PID:292763; identified by sequence similarity; putative. | Riboflavin synthase, alpha subunit; See PMID:20190049 for expression data. | 0.929 |
| AAO54375.1 | ribH-1 | PSPTO_0835 | PSPTO_0693 | ribD C-terminal domain protein; See PMID:20190049 for expression data; similar to GB:S69136, GB:S69198, GB:M28594, and PID:292763; identified by sequence similarity; putative. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.866 |
| AAO54375.1 | ribH-2 | PSPTO_0835 | PSPTO_1839 | ribD C-terminal domain protein; See PMID:20190049 for expression data; similar to GB:S69136, GB:S69198, GB:M28594, and PID:292763; identified by sequence similarity; putative. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.723 |
| nrdR | ribA | PSPTO_0689 | PSPTO_0696 | Conserved protein of unknown function; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.601 |
| nrdR | ribBA-1 | PSPTO_0689 | PSPTO_0692 | Conserved protein of unknown function; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.783 |
| nrdR | ribBA-2 | PSPTO_0689 | PSPTO_2668 | Conserved protein of unknown function; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | 0.504 |
| nrdR | ribD | PSPTO_0689 | PSPTO_0690 | Conserved protein of unknown function; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.963 |
| nrdR | ribE | PSPTO_0689 | PSPTO_0691 | Conserved protein of unknown function; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | Riboflavin synthase, alpha subunit; See PMID:20190049 for expression data. | 0.863 |
| nrdR | ribF | PSPTO_0689 | PSPTO_0805 | Conserved protein of unknown function; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | Riboflavin biosynthesis protein RibF; See PMID:20190049 for expression data; Belongs to the ribF family. | 0.650 |
| nrdR | ribH-1 | PSPTO_0689 | PSPTO_0693 | Conserved protein of unknown function; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.536 |
| ribA | AAO54375.1 | PSPTO_0696 | PSPTO_0835 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | ribD C-terminal domain protein; See PMID:20190049 for expression data; similar to GB:S69136, GB:S69198, GB:M28594, and PID:292763; identified by sequence similarity; putative. | 0.982 |