Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
gene fusions
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AAO54408.1Nikkomycin biosynthesis domain protein; See PMID:20190049 for expression data; similar to GP:14030855; identified by sequence similarity; putative. (417 aa)    
Predicted Functional Partners:
oadA
Oxaloacetate decarboxylase, alpha subunit; See PMID:20190049 for expression data.
  
 
 0.799
AAO57967.1
This gene is aparrently the terminal component of a non-ribosomal peptide synthetase (due to the presence of the terminal thioesterase domain) and is most likely associated with the previous gene which appears to be a initiating component. This gene contains three complete amino acid activation, thiolation and condensation domain modules and appears to be specific for glycine, an unidentified amino acid and serine according to the prediction algorithm at http://raynam.chm.jhu.edu/; nrps/index2.html. Taken together these two genes appear to direct the biosynthesis of a previously undesc [...]
 
   
 0.695
cmaA
Coronamic acid synthetase CmaA; Non-ribosomal peptide synthetase with adenylation and thiolation domains; reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis; see PMID: 14679222; see PMID:20190049 for expression data; non-ribosomal peptide synthetase with adenylation and thiolation domains, reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis, see PMID: 14679222.
     
 0.654
cfa6
Coronafacic acid polyketide synthase I; This gene is the first of two multimodular polyketide synthetases involved in the biosynthesis of coronafacic acid. This synthetase is proposed to receive CPC (2-carboxy-2-cyclopentenone) from an acyl carrier protein (cfa1), it then adds a buyrate group and then completely reduces the ketone of the (former) carboxylate group. The resulting product is then passed to the second polyketide synthetase (cfa7); similar to GP:13346874; identified by sequence similarity; putative; see PMID:20190049 for expression data; This gene is the first of two multi [...]
 
  
 0.635
AAO54409.1
Conserved protein of unknown function; Also known as Ipx47 (PMID11967070; Boch et al, 2002); see PMID:20190049 for expression data; similar to GP:14030855; identified by sequence similarity; putative.
 
    
0.621
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
   
   0.612
AAO53748.1
Conserved protein of unknown function; See PMID:20190049 for expression data; similar to GP:11071202; identified by sequence similarity; putative.
 
     0.590
AAO54407.1
Amidinotransferase family protein; Similar to GP:5919222, GB:M13699, GB:D00025, GB:X69706, GB:M13536, GB:X04136, GB:X04137, GB:X04138, SP:P00450, PID:1335036, PID:1335037, PID:1666064, and PID:180249; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to GP:5919222, GB:M13699, GB:D00025, GB:X69706, GB:M13536, GB:X04136, GB:X04137, GB:X04138, SP:P00450, PID:1335036, PID:1335037, PID:1666064, and PID:180249, identified by sequence similarity, putative.
     
 0.574
mdcE
Malonate decarboxylase, gamma subunit; Similar to GP:4062977, and GP:2240015; identified by sequence similarity; putative.
 
 
 0.550
mdcD
Malonate decarboxylase, beta subunit; Similar to GP:2240014; identified by sequence similarity; putative.
 
 
 0.537
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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