Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pgiGlucose-6-phosphate isomerase; Identified by match to PFAM protein family HMM PF00342; see PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF00342. (554 aa)    
Predicted Functional Partners:
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 0.996
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
 
 0.992
pgm
Phosphoglucomutase, alpha-D-glucose phosphate-specific; See PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF02878.
 
 0.985
pyk
Pyruvate kinase; Identified by match to PFAM protein family HMM PF02887; Belongs to the pyruvate kinase family.
 
 0.982
gap-1
Glyceraldehyde 3-phosphate dehydrogenase, type I; See PMID:20190049 for expression data; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
 0.978
fba
Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
  
 0.975
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.971
glk
Glucokinase; See PMID:20190049 for expression data; Belongs to the bacterial glucokinase family.
    
 0.968
fbp
Fructose-1,6-bisphosphatase; Similar to SP:P19911; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to SP:P19911, identified by sequence similarity, putative.
  
 
 0.967
eno-1
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
  
 0.965
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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