| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AAO53946.1 | msrQ | PSPTO_0402 | PSPTO_0986 | Iron-sulfur cluster-binding protein; Similar to GP:15073802; identified by sequence similarity; putative. | Membrane protein, putative; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, usi [...] | 0.527 |
| AAO57074.1 | AAO57134.1 | PSPTO_3600 | PSPTO_3665 | Oxidoreductase, molybdopterin-binding protein; See PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF00174. | Conserved protein of unknown function; See PMID:20190049 for expression data; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | 0.440 |
| AAO57074.1 | moaE | PSPTO_3600 | PSPTO_1249 | Oxidoreductase, molybdopterin-binding protein; See PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF00174. | Molybdenum cofactor biosynthesis protein E; See PMID:20190049 for expression data. | 0.453 |
| AAO57074.1 | msrQ | PSPTO_3600 | PSPTO_0986 | Oxidoreductase, molybdopterin-binding protein; See PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF00174. | Membrane protein, putative; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, usi [...] | 0.918 |
| AAO57134.1 | AAO57074.1 | PSPTO_3665 | PSPTO_3600 | Conserved protein of unknown function; See PMID:20190049 for expression data; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | Oxidoreductase, molybdopterin-binding protein; See PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF00174. | 0.440 |
| AAO57134.1 | msrP | PSPTO_3665 | PSPTO_0985 | Conserved protein of unknown function; See PMID:20190049 for expression data; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | Conserved protein of unknown function; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce [...] | 0.440 |
| AAO57134.1 | msrQ | PSPTO_3665 | PSPTO_0986 | Conserved protein of unknown function; See PMID:20190049 for expression data; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | Membrane protein, putative; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, usi [...] | 0.665 |
| ilvC | ilvN | PSPTO_0983 | PSPTO_0982 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Acetolactate synthase, small subunit; Similar to SP:P00894; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to SP:P00894, identified by sequence similarity, putative. | 0.998 |
| ilvC | msrP | PSPTO_0983 | PSPTO_0985 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Conserved protein of unknown function; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce [...] | 0.479 |
| ilvC | msrQ | PSPTO_0983 | PSPTO_0986 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Membrane protein, putative; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, usi [...] | 0.694 |
| ilvC | pssA-1 | PSPTO_0983 | PSPTO_0984 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | CDP-diacylglycerol--serine O-phosphatidyltransferase; See PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR00560; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.744 |
| ilvN | ilvC | PSPTO_0982 | PSPTO_0983 | Acetolactate synthase, small subunit; Similar to SP:P00894; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to SP:P00894, identified by sequence similarity, putative. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.998 |
| ilvN | msrP | PSPTO_0982 | PSPTO_0985 | Acetolactate synthase, small subunit; Similar to SP:P00894; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to SP:P00894, identified by sequence similarity, putative. | Conserved protein of unknown function; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce [...] | 0.418 |
| ilvN | msrQ | PSPTO_0982 | PSPTO_0986 | Acetolactate synthase, small subunit; Similar to SP:P00894; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to SP:P00894, identified by sequence similarity, putative. | Membrane protein, putative; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, usi [...] | 0.460 |
| ilvN | pssA-1 | PSPTO_0982 | PSPTO_0984 | Acetolactate synthase, small subunit; Similar to SP:P00894; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to SP:P00894, identified by sequence similarity, putative. | CDP-diacylglycerol--serine O-phosphatidyltransferase; See PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR00560; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.704 |
| moaD | moaE | PSPTO_1248 | PSPTO_1249 | Molybdenum cofactor biosynthesis protein D; See PMID:20190049 for expression data. | Molybdenum cofactor biosynthesis protein E; See PMID:20190049 for expression data. | 0.999 |
| moaD | msrQ | PSPTO_1248 | PSPTO_0986 | Molybdenum cofactor biosynthesis protein D; See PMID:20190049 for expression data. | Membrane protein, putative; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, usi [...] | 0.445 |
| moaE | AAO57074.1 | PSPTO_1249 | PSPTO_3600 | Molybdenum cofactor biosynthesis protein E; See PMID:20190049 for expression data. | Oxidoreductase, molybdopterin-binding protein; See PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF00174. | 0.453 |
| moaE | moaD | PSPTO_1249 | PSPTO_1248 | Molybdenum cofactor biosynthesis protein E; See PMID:20190049 for expression data. | Molybdenum cofactor biosynthesis protein D; See PMID:20190049 for expression data. | 0.999 |
| moaE | msrP | PSPTO_1249 | PSPTO_0985 | Molybdenum cofactor biosynthesis protein E; See PMID:20190049 for expression data. | Conserved protein of unknown function; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce [...] | 0.417 |
