node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAO55061.1 | cdsA-1 | PSPTO_1541 | PSPTO_1539 | Membrane-associated zinc metalloprotease, putative; See PMID:20190049 for expression data. | Phosphatidate cytidylyltransferase; See PMID:20190049 for expression data; Belongs to the CDS family. | 0.774 |
AAO55061.1 | dxr | PSPTO_1541 | PSPTO_1540 | Membrane-associated zinc metalloprotease, putative; See PMID:20190049 for expression data. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.753 |
AAO55061.1 | frr | PSPTO_1541 | PSPTO_1537 | Membrane-associated zinc metalloprotease, putative; See PMID:20190049 for expression data. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.698 |
AAO55061.1 | proS | PSPTO_1541 | PSPTO_3988 | Membrane-associated zinc metalloprotease, putative; See PMID:20190049 for expression data. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] | 0.471 |
AAO55061.1 | pyrH | PSPTO_1541 | PSPTO_1536 | Membrane-associated zinc metalloprotease, putative; See PMID:20190049 for expression data. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.689 |
AAO55061.1 | tsf | PSPTO_1541 | PSPTO_1535 | Membrane-associated zinc metalloprotease, putative; See PMID:20190049 for expression data. | Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.452 |
AAO55061.1 | uppS | PSPTO_1541 | PSPTO_1538 | Membrane-associated zinc metalloprotease, putative; See PMID:20190049 for expression data. | Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.849 |
cdsA-1 | AAO55061.1 | PSPTO_1539 | PSPTO_1541 | Phosphatidate cytidylyltransferase; See PMID:20190049 for expression data; Belongs to the CDS family. | Membrane-associated zinc metalloprotease, putative; See PMID:20190049 for expression data. | 0.774 |
cdsA-1 | dxr | PSPTO_1539 | PSPTO_1540 | Phosphatidate cytidylyltransferase; See PMID:20190049 for expression data; Belongs to the CDS family. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.931 |
cdsA-1 | frr | PSPTO_1539 | PSPTO_1537 | Phosphatidate cytidylyltransferase; See PMID:20190049 for expression data; Belongs to the CDS family. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.890 |
cdsA-1 | pyrH | PSPTO_1539 | PSPTO_1536 | Phosphatidate cytidylyltransferase; See PMID:20190049 for expression data; Belongs to the CDS family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.944 |
cdsA-1 | tsf | PSPTO_1539 | PSPTO_1535 | Phosphatidate cytidylyltransferase; See PMID:20190049 for expression data; Belongs to the CDS family. | Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.660 |
cdsA-1 | uppS | PSPTO_1539 | PSPTO_1538 | Phosphatidate cytidylyltransferase; See PMID:20190049 for expression data; Belongs to the CDS family. | Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.984 |
dxr | AAO55061.1 | PSPTO_1540 | PSPTO_1541 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Membrane-associated zinc metalloprotease, putative; See PMID:20190049 for expression data. | 0.753 |
dxr | cdsA-1 | PSPTO_1540 | PSPTO_1539 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Phosphatidate cytidylyltransferase; See PMID:20190049 for expression data; Belongs to the CDS family. | 0.931 |
dxr | frr | PSPTO_1540 | PSPTO_1537 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.850 |
dxr | ispA | PSPTO_1540 | PSPTO_0699 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Geranyltranstransferase; See PMID:20190049 for expression data; Belongs to the FPP/GGPP synthase family. | 0.542 |
dxr | proS | PSPTO_1540 | PSPTO_3988 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] | 0.453 |
dxr | pyrH | PSPTO_1540 | PSPTO_1536 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.819 |
dxr | tsf | PSPTO_1540 | PSPTO_1535 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.693 |