Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pobRTranscriptional regulator PobR. (289 aa)    
Predicted Functional Partners:
pobA
P-hydroxybenzoate hydroxylase.
 
   
 0.967
pcaQ
Pca operon transcriptional activator PcaQ; See PMID:20190049 for expression data; similar to GP:10442737, and SP:P52668; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
 
  
 0.932
vanR
Transcriptional regulator VanR; See PMID:20190049 for expression data.
 
  
 0.854
pcaR
Pca regulon regulatory protein PcaR; See PMID:20190049 for expression data; similar to GP:6646870, and SP:Q52154; identified by sequence similarity; putative.
 
  
 0.731
pcaG
Protocatechuate 3,4-dioxygenase, alpha subunit; See PMID:20190049 for expression data; similar to GP:10442739, and SP:P00436; identified by sequence similarity; putative.
 
   
 0.723
AAO57967.1
This gene is aparrently the terminal component of a non-ribosomal peptide synthetase (due to the presence of the terminal thioesterase domain) and is most likely associated with the previous gene which appears to be a initiating component. This gene contains three complete amino acid activation, thiolation and condensation domain modules and appears to be specific for glycine, an unidentified amino acid and serine according to the prediction algorithm at http://raynam.chm.jhu.edu/; nrps/index2.html. Taken together these two genes appear to direct the biosynthesis of a previously undesc [...]
  
  
 0.723
cmaA
Coronamic acid synthetase CmaA; Non-ribosomal peptide synthetase with adenylation and thiolation domains; reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis; see PMID: 14679222; see PMID:20190049 for expression data; non-ribosomal peptide synthetase with adenylation and thiolation domains, reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis, see PMID: 14679222.
  
  
 0.723
cfa6
Coronafacic acid polyketide synthase I; This gene is the first of two multimodular polyketide synthetases involved in the biosynthesis of coronafacic acid. This synthetase is proposed to receive CPC (2-carboxy-2-cyclopentenone) from an acyl carrier protein (cfa1), it then adds a buyrate group and then completely reduces the ketone of the (former) carboxylate group. The resulting product is then passed to the second polyketide synthetase (cfa7); similar to GP:13346874; identified by sequence similarity; putative; see PMID:20190049 for expression data; This gene is the first of two multi [...]
  
  
 0.718
pcaH
Protocatechuate 3,4-dioxygenase, beta subunit; Similar to SP:P00437, GB:M30496, SP:P15374, and PID:340074; identified by sequence similarity; putative.
 
   
 0.690
lrp
Leucine-responsive regulatory protein; See PMID:20190049 for expression data; similar to SP:P37403; identified by sequence similarity; putative.
   
  
 0.643
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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