Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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acnAAconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (914 aa)    
Predicted Functional Partners:
gltA
Citrate synthase I; Similar to PIR:A33596; identified by sequence similarity; putative; Belongs to the citrate synthase family.
 
 0.992
prpC
2-methylcitrate synthase; See PMID:20190049 for expression data; Belongs to the citrate synthase family.
 
 0.990
AAO55804.1
Conserved hypothetical protein.
 
 
 0.974
acnB
Aconitate hydratase 2; Identified by match to TIGR protein family HMM TIGR01342; see PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01342; Belongs to the aconitase/IPM isomerase family.
    
 0.964
prpB
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
 
 0.944
AAO56834.1
Isocitrate dehydrogenase, NADP-dependent; See PMID:20190049 for expression data; Belongs to the monomeric-type IDH family.
  
 
 0.924
aceA
Isocitrate lyase.
   
 
 0.923
AAO55533.1
CAAX amino terminal protease family protein; Identified by match to PFAM protein family HMM PF02517.
     
 0.899
sucA
2-oxoglutarate dehydrogenase, E1 component; Identified by match to PFAM protein family HMM PF02779; see PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF02779.
 
 0.895
fumC-1
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.854
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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