Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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daT2,4-diaminobutyrate 4-transaminase; Catalyzes the conversion of aspartate semialdehyde (an intermediate in the biosynthesis of various amino acids) to 2,4-diaminobutyrate (DAB). It is unclear whether the partner for this converison is alanine or glutamate. DAB is required for the biosynthesis of the pyoverdine chromophore, and this gene is located whithin the pyoverdine gene cluster; similar to SP:P56744; identified by sequence similarity; putative; see PMID:20190049 for expression data; Catalyzes the conversion of aspartate semialdehyde (an intermediate in the biosynthesis of various [...] (488 aa)    
Predicted Functional Partners:
pvsA
Pyoverdine chromophore precursor synthetase; This synthetase is the first component (of five) in the biosynthesis of the P. syringae pyoverdine peptide which is subsequently modified by various enzymes to produce the mature pyoverdine siderophore. This module initiates the chain and synthesizes the tripeptide L-glutamate:D-tyrosine:L-2-diaminobutyrate which is the constant feature of all pyoverdines and is subsequently converted to the fluorescent chromophore; see PMID:20190049 for expression data; similar to GP:440169; identified by sequence similarity; putative.
 
  
 0.960
AAO55672.1
Aminotransferase, class V; See PMID:20190049 for expression data; similar to GP:13506638; identified by sequence similarity; putative.
  
  
 0.924
hom
Homoserine dehydrogenase; See PMID:20190049 for expression data.
     
 0.916
AAO57967.1
This gene is aparrently the terminal component of a non-ribosomal peptide synthetase (due to the presence of the terminal thioesterase domain) and is most likely associated with the previous gene which appears to be a initiating component. This gene contains three complete amino acid activation, thiolation and condensation domain modules and appears to be specific for glycine, an unidentified amino acid and serine according to the prediction algorithm at http://raynam.chm.jhu.edu/; nrps/index2.html. Taken together these two genes appear to direct the biosynthesis of a previously undesc [...]
 
  
 0.913
AAO55671.1
Conserved protein of unknown function; See PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF03781.
   
  
 0.910
asd-1
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
    
 0.908
pvdQ
Penicillin amidase family protein; Catalyzes the deacylation of acyl-homoserine lactone (AHL or acyl-HSL), releasing homoserine lactone (HSL) and the corresponding fatty acid. Possesses a specificity for the degradation of long-chain acyl-HSLs (side chains of 11 to 14 carbons in length) (By similarity).
  
  
 0.907
AAO55654.1
MbtH-like protein; See PMID:20190049 for expression data; similar to GP:15159638; identified by sequence similarity; putative.
 
  
 0.879
cmaA
Coronamic acid synthetase CmaA; Non-ribosomal peptide synthetase with adenylation and thiolation domains; reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis; see PMID: 14679222; see PMID:20190049 for expression data; non-ribosomal peptide synthetase with adenylation and thiolation domains, reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis, see PMID: 14679222.
  
  
 0.859
pvdE
Pyoverdine ABC transporter, ATP-binding/permease protein; See PMID:20190049 for expression data; similar to GP:466460, GB:X06325, SP:P09002, and PID:1333690; identified by sequence similarity; putative.
  
  
 0.843
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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