Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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AAO55664.1This synthetase is the second module (of five) in the biosynthesis of the P. syringae pyoverdine peptide which is subsequently modified by various enzymes to produce the mature pyoverdine siderophore; see PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01734. (1104 aa)    
Predicted Functional Partners:
AAO55663.1
Pyoverdine biosynthesis regulatory gene, putative; Present adjacent to pyoverdine biosynthetic genes; similar to GP:1890776; identified by sequence similarity; putative; see PMID:20190049 for expression data; Present adjacent to pyoverdine biosynthetic genes, see PMID:20190049 for expression data; similar to GP:1890776, identified by sequence similarity, putative.
  
 0.982
cmaA
Coronamic acid synthetase CmaA; Non-ribosomal peptide synthetase with adenylation and thiolation domains; reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis; see PMID: 14679222; see PMID:20190049 for expression data; non-ribosomal peptide synthetase with adenylation and thiolation domains, reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis, see PMID: 14679222.
 
 
0.973
cfa7
Coronafacic acid polyketide synthetase II; This gene is the second of two multimodular polyketide synthetases involved in the biosynthesis of coronafacic acid. This synthetase is proposed to receive CPE (2-[1-oxo-2-cyclopenten-2-ylmethyl]butanoic acid) from the first synthetase, Cpe6. It then adds one final acetate group, catalyzes the cyclization of the second ring and converts a ketone to a double bond. The product is released by a terminal thioesterase domain; similar to GP:13162634; identified by sequence similarity; putative; see PMID:20190049 for expression data; This gene is the [...]
  
 0.971
AAO57967.1
This gene is aparrently the terminal component of a non-ribosomal peptide synthetase (due to the presence of the terminal thioesterase domain) and is most likely associated with the previous gene which appears to be a initiating component. This gene contains three complete amino acid activation, thiolation and condensation domain modules and appears to be specific for glycine, an unidentified amino acid and serine according to the prediction algorithm at http://raynam.chm.jhu.edu/; nrps/index2.html. Taken together these two genes appear to direct the biosynthesis of a previously undesc [...]
 
 
0.968
cfa6
Coronafacic acid polyketide synthase I; This gene is the first of two multimodular polyketide synthetases involved in the biosynthesis of coronafacic acid. This synthetase is proposed to receive CPC (2-carboxy-2-cyclopentenone) from an acyl carrier protein (cfa1), it then adds a buyrate group and then completely reduces the ketone of the (former) carboxylate group. The resulting product is then passed to the second polyketide synthetase (cfa7); similar to GP:13346874; identified by sequence similarity; putative; see PMID:20190049 for expression data; This gene is the first of two multi [...]
 
 0.948
AAO55654.1
MbtH-like protein; See PMID:20190049 for expression data; similar to GP:15159638; identified by sequence similarity; putative.
 
 
 0.893
AAO57969.1
Conserved protein of unknown function; See PMID:20190049 for expression data; similar to GP:9937237, and GP:17431110; identified by sequence similarity; putative.
 
 
 0.892
AAO58342.1
Oxidoreductase, short chain dehydrogenase/reductase family; See PMID:20190049 for expression data.
      0.875
AAO55651.1
Pyoverdine synthetase, thioesterase component; Presumed to be involved in the biosynthesis of pyoverdine due to proximity to the rest of the pyoverdine biosynthetic gene cluster. Possibly acts to release the pyoverdine chromophore precursor from PvsA; see PMID:20190049 for expression data; similar to GP:9948471; identified by sequence similarity; putative.
 
  
 0.874
irp4
Yersiniabactin synthetase, thioesterase component; Possibly involved in the release of an intermediate product see PMID:20190049 for expression data; similar to pyochelin, since the terminal yersiniabactin synthetase has its own thioesterase domain; see PMID:20190049 for expression data; similar to GP:3818607; identified by sequence similarity; putative.
 
  
 0.869
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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