Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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pvdEPyoverdine ABC transporter, ATP-binding/permease protein; See PMID:20190049 for expression data; similar to GP:466460, GB:X06325, SP:P09002, and PID:1333690; identified by sequence similarity; putative. (554 aa)    
Predicted Functional Partners:
AAO57967.1
This gene is aparrently the terminal component of a non-ribosomal peptide synthetase (due to the presence of the terminal thioesterase domain) and is most likely associated with the previous gene which appears to be a initiating component. This gene contains three complete amino acid activation, thiolation and condensation domain modules and appears to be specific for glycine, an unidentified amino acid and serine according to the prediction algorithm at http://raynam.chm.jhu.edu/; nrps/index2.html. Taken together these two genes appear to direct the biosynthesis of a previously undesc [...]
 
  
 0.979
cmaA
Coronamic acid synthetase CmaA; Non-ribosomal peptide synthetase with adenylation and thiolation domains; reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis; see PMID: 14679222; see PMID:20190049 for expression data; non-ribosomal peptide synthetase with adenylation and thiolation domains, reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis, see PMID: 14679222.
 
  
 0.962
pvsA
Pyoverdine chromophore precursor synthetase; This synthetase is the first component (of five) in the biosynthesis of the P. syringae pyoverdine peptide which is subsequently modified by various enzymes to produce the mature pyoverdine siderophore. This module initiates the chain and synthesizes the tripeptide L-glutamate:D-tyrosine:L-2-diaminobutyrate which is the constant feature of all pyoverdines and is subsequently converted to the fluorescent chromophore; see PMID:20190049 for expression data; similar to GP:440169; identified by sequence similarity; putative.
 
  
 0.948
AAO55671.1
Conserved protein of unknown function; See PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF03781.
  
  
 0.945
AAO55672.1
Aminotransferase, class V; See PMID:20190049 for expression data; similar to GP:13506638; identified by sequence similarity; putative.
  
  
 0.942
AAO55666.1
Pyoverdine sidechain peptide synthetase III, L-Thr-L-Ser component; This synthetase is the fourth module (of five) in the biosynthesis of the P. syringae pyoverdine peptide which is subsequently modified by various enzymes to produce the mature pyoverdine siderophore; see PMID:20190049 for expression data; similar to GP:13094061; identified by sequence similarity; putative.
 
  
 0.918
syfA
Non-ribosomal peptide synthetase SyfA; This gene consists of three complete condensation, adenylation, thiolation domain modules. The adenylation domains are specific for leucine, leucine and glutamine; together with PSPTO_2830 codes for proteins involved in production of lipopeptide syringofactins. See PMID:17601782.
 
  
 0.908
AAO58141.1
Non-ribosomal peptide synthetase, terminal component; This gene consists of four complete condensation-amino acid adenylation/ligation-thiolation modules followed by a thioesterase. The initial condensation domain implies that another thiolation domain-containing protein precedes this one in the functional complex although no such component is found upstream of this gene. This gene is found within the coronatine biosynthesis gene cluster and does not appear to be functionally related to those genes. Prediction of amino acid specificities at http://raynam.chm.jhu.edu/; nrps/index2.html [...]
 
  
 0.907
syfB
Non-ribosomal peptide synthetase SyfB; This gene consists of five complete condensation, adenylation, thiolation domain modules followed by two thioesterase domains. The adenylation domains are specific for leucine, threonine, valine, leucine and leucine; together with PSPTO_2829 codes for proteins involved in production of lipopeptide syringofactins. See PMID:17601782.
 
  
 0.904
AAO55673.1
Renal dipeptidase family protein; See PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF02776.
  
  
 0.901
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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