Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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macB1Macrolide ABC efflux protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (656 aa)    
Predicted Functional Partners:
AAO55675.1
Outer membrane efflux protein; See PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF02321.
 
 
 0.993
AAO55677.1
Efflux transporter, RND family, MFP subunit; See PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01730; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.992
syfD
Syringafactin efflux protein SyfD; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
0.992
syfC
Syringafactin efflux protein SyfC; See PMID:17601782; see PMID:20190049 for expression data; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.968
AAO55209.1
Lipoprotein, putative.
 
 
   0.804
AAO56097.1
Multidrug resistance protein, AcrA/AcrE family; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.798
AAO57754.1
Efflux transporter, RND family, MFP subunit; See PMID:20190049 for expression data; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.798
pvdQ
Penicillin amidase family protein; Catalyzes the deacylation of acyl-homoserine lactone (AHL or acyl-HSL), releasing homoserine lactone (HSL) and the corresponding fatty acid. Possesses a specificity for the degradation of long-chain acyl-HSLs (side chains of 11 to 14 carbons in length) (By similarity).
  
  
 0.796
mexE
Multidrug efflux RND membrane fusion protein MexE; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.793
AAO57967.1
This gene is aparrently the terminal component of a non-ribosomal peptide synthetase (due to the presence of the terminal thioesterase domain) and is most likely associated with the previous gene which appears to be a initiating component. This gene contains three complete amino acid activation, thiolation and condensation domain modules and appears to be specific for glycine, an unidentified amino acid and serine according to the prediction algorithm at http://raynam.chm.jhu.edu/; nrps/index2.html. Taken together these two genes appear to direct the biosynthesis of a previously undesc [...]
  
 
 0.761
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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