Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
aspCAspartate aminotransferase; See PMID:20190049 for expression data. (398 aa)    
Predicted Functional Partners:
pheA
Chorismate mutase/prephenate dehydratase; See PMID:20190049 for expression data.
    
 0.969
hppD
4-hydroxyphenylpyruvate dioxygenase; Identified by match to PFAM protein family HMM PF00903; see PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF00903.
  
 
 0.955
phhA
Phenylalanine-4-hydroxylase; Identified by match to TIGR protein family HMM TIGR01270.
  
 
 0.948
AAO55268.1
Prephenate dehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase family protein; See PMID:20190049 for expression data.
    
 0.940
hisC
Histidinol-phosphate aminotransferase; Identified by match to TIGR protein family HMM TIGR01265; see PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01265; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
   
 
 0.924
aspB
Aspartate aminotransferase; Similar to SP:P53001; identified by sequence similarity; putative.
   
 0.920
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.915
mtnD
ARD/ARD' family protein; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
     
 0.914
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
     
 0.909
aroH
Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate.
    
 0.907
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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