Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AAO55712.1Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (122 aa)    
Predicted Functional Partners:
sdhC
Succinate dehydrogenase, cytochrome b556 subunit; See PMID:20190049 for expression data; similar to GP:9947544, and SP:P10446; identified by sequence similarity; putative.
 
 0.999
sdhA
Succinate dehydrogenase, flavoprotein subunit; Similar to SP:P10444, GB:D12485, GB:M57736, SP:P22413, PID:189650, PID:219944, and PID:219945; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to SP:P10444, GB:D12485, GB:M57736, SP:P22413, PID:189650, PID:219944, and PID:219945, identified by sequence similarity, putative; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 0.999
sdhB
Succinate dehydrogenase, iron-sulfur protein; Similar to SP:P07014, GB:L05004, and PID:152957; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to SP:P07014, GB:L05004, and PID:152957, identified by sequence similarity, putative.
 
 0.999
sucC
succinyl-CoA synthase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.996
AAO57790.1
Fumarate hydratase, class I, putative; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.985
sucD
succinyl-CoA synthase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.980
sucA
2-oxoglutarate dehydrogenase, E1 component; Identified by match to PFAM protein family HMM PF02779; see PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF02779.
  
  
 0.953
gabD-1
Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
 0.936
gabD-3
Succinate-semialdehyde dehydrogenase; See PMID:20190049 for expression data; similar to GP:15140237, and SP:P25526; identified by sequence similarity; putative.
   
 
 0.936
nuoCD
NADH dehydrogenase I, C/D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
  
 0.933
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.