node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAO55651.1 | AAO55654.1 | PSPTO_2134 | PSPTO_2137 | Pyoverdine synthetase, thioesterase component; Presumed to be involved in the biosynthesis of pyoverdine due to proximity to the rest of the pyoverdine biosynthetic gene cluster. Possibly acts to release the pyoverdine chromophore precursor from PvsA; see PMID:20190049 for expression data; similar to GP:9948471; identified by sequence similarity; putative. | MbtH-like protein; See PMID:20190049 for expression data; similar to GP:15159638; identified by sequence similarity; putative. | 0.874 |
AAO55651.1 | AAO57966.1 | PSPTO_2134 | PSPTO_4518 | Pyoverdine synthetase, thioesterase component; Presumed to be involved in the biosynthesis of pyoverdine due to proximity to the rest of the pyoverdine biosynthetic gene cluster. Possibly acts to release the pyoverdine chromophore precursor from PvsA; see PMID:20190049 for expression data; similar to GP:9948471; identified by sequence similarity; putative. | This gene is aparrently the initiating component of a non-ribosomal peptide synthetase (due to the presence of an initial non-amino acid adenylation/ligase domain) and is most likely associated with the following gene which appears to be a terminating component. This gene contains a thiolation domain as well as one complete amino acid activation, thiolation and condensation domain modules which appears to be specific for serine according to the prediction algorithm at http://raynam.chm.jhu.edu/; nrps/index2.html. Taken together these two genes appear to direct the biosynthesis of a pre [...] | 0.895 |
AAO55651.1 | AAO57967.1 | PSPTO_2134 | PSPTO_4519 | Pyoverdine synthetase, thioesterase component; Presumed to be involved in the biosynthesis of pyoverdine due to proximity to the rest of the pyoverdine biosynthetic gene cluster. Possibly acts to release the pyoverdine chromophore precursor from PvsA; see PMID:20190049 for expression data; similar to GP:9948471; identified by sequence similarity; putative. | This gene is aparrently the terminal component of a non-ribosomal peptide synthetase (due to the presence of the terminal thioesterase domain) and is most likely associated with the previous gene which appears to be a initiating component. This gene contains three complete amino acid activation, thiolation and condensation domain modules and appears to be specific for glycine, an unidentified amino acid and serine according to the prediction algorithm at http://raynam.chm.jhu.edu/; nrps/index2.html. Taken together these two genes appear to direct the biosynthesis of a previously undesc [...] | 0.994 |
AAO55651.1 | AAO57969.1 | PSPTO_2134 | PSPTO_4521 | Pyoverdine synthetase, thioesterase component; Presumed to be involved in the biosynthesis of pyoverdine due to proximity to the rest of the pyoverdine biosynthetic gene cluster. Possibly acts to release the pyoverdine chromophore precursor from PvsA; see PMID:20190049 for expression data; similar to GP:9948471; identified by sequence similarity; putative. | Conserved protein of unknown function; See PMID:20190049 for expression data; similar to GP:9937237, and GP:17431110; identified by sequence similarity; putative. | 0.831 |
AAO55651.1 | cfa6 | PSPTO_2134 | PSPTO_4686 | Pyoverdine synthetase, thioesterase component; Presumed to be involved in the biosynthesis of pyoverdine due to proximity to the rest of the pyoverdine biosynthetic gene cluster. Possibly acts to release the pyoverdine chromophore precursor from PvsA; see PMID:20190049 for expression data; similar to GP:9948471; identified by sequence similarity; putative. | Coronafacic acid polyketide synthase I; This gene is the first of two multimodular polyketide synthetases involved in the biosynthesis of coronafacic acid. This synthetase is proposed to receive CPC (2-carboxy-2-cyclopentenone) from an acyl carrier protein (cfa1), it then adds a buyrate group and then completely reduces the ketone of the (former) carboxylate group. The resulting product is then passed to the second polyketide synthetase (cfa7); similar to GP:13346874; identified by sequence similarity; putative; see PMID:20190049 for expression data; This gene is the first of two multi [...] | 0.947 |
AAO55651.1 | cfa7 | PSPTO_2134 | PSPTO_4687 | Pyoverdine synthetase, thioesterase component; Presumed to be involved in the biosynthesis of pyoverdine due to proximity to the rest of the pyoverdine biosynthetic gene cluster. Possibly acts to release the pyoverdine chromophore precursor from PvsA; see PMID:20190049 for expression data; similar to GP:9948471; identified by sequence similarity; putative. | Coronafacic acid polyketide synthetase II; This gene is the second of two multimodular polyketide synthetases involved in the biosynthesis of coronafacic acid. This synthetase is proposed to receive CPE (2-[1-oxo-2-cyclopenten-2-ylmethyl]butanoic acid) from the first synthetase, Cpe6. It then adds one final acetate group, catalyzes the cyclization of the second ring and converts a ketone to a double bond. The product is released by a terminal thioesterase domain; similar to GP:13162634; identified by sequence similarity; putative; see PMID:20190049 for expression data; This gene is the [...] | 0.857 |
AAO55651.1 | cmaA | PSPTO_2134 | PSPTO_4709 | Pyoverdine synthetase, thioesterase component; Presumed to be involved in the biosynthesis of pyoverdine due to proximity to the rest of the pyoverdine biosynthetic gene cluster. Possibly acts to release the pyoverdine chromophore precursor from PvsA; see PMID:20190049 for expression data; similar to GP:9948471; identified by sequence similarity; putative. | Coronamic acid synthetase CmaA; Non-ribosomal peptide synthetase with adenylation and thiolation domains; reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis; see PMID: 14679222; see PMID:20190049 for expression data; non-ribosomal peptide synthetase with adenylation and thiolation domains, reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis, see PMID: 14679222. | 0.993 |
AAO55651.1 | mgoA | PSPTO_2134 | PSPTO_5457 | Pyoverdine synthetase, thioesterase component; Presumed to be involved in the biosynthesis of pyoverdine due to proximity to the rest of the pyoverdine biosynthetic gene cluster. Possibly acts to release the pyoverdine chromophore precursor from PvsA; see PMID:20190049 for expression data; similar to GP:9948471; identified by sequence similarity; putative. | Ornithine acetyl transferase inhibitor; This enzyme consists of an amino acid activation and ligation domain followed by a thiolation domaintypical of non-ribosomal peptide synthetases; similar to the ornithine acetyl transferase inhibitor mangotoxin; see PMID:17506328. | 0.938 |
AAO55651.1 | syfB | PSPTO_2134 | PSPTO_2830 | Pyoverdine synthetase, thioesterase component; Presumed to be involved in the biosynthesis of pyoverdine due to proximity to the rest of the pyoverdine biosynthetic gene cluster. Possibly acts to release the pyoverdine chromophore precursor from PvsA; see PMID:20190049 for expression data; similar to GP:9948471; identified by sequence similarity; putative. | Non-ribosomal peptide synthetase SyfB; This gene consists of five complete condensation, adenylation, thiolation domain modules followed by two thioesterase domains. The adenylation domains are specific for leucine, threonine, valine, leucine and leucine; together with PSPTO_2829 codes for proteins involved in production of lipopeptide syringofactins. See PMID:17601782. | 0.892 |
AAO55654.1 | AAO55651.1 | PSPTO_2137 | PSPTO_2134 | MbtH-like protein; See PMID:20190049 for expression data; similar to GP:15159638; identified by sequence similarity; putative. | Pyoverdine synthetase, thioesterase component; Presumed to be involved in the biosynthesis of pyoverdine due to proximity to the rest of the pyoverdine biosynthetic gene cluster. Possibly acts to release the pyoverdine chromophore precursor from PvsA; see PMID:20190049 for expression data; similar to GP:9948471; identified by sequence similarity; putative. | 0.874 |
AAO55654.1 | AAO57966.1 | PSPTO_2137 | PSPTO_4518 | MbtH-like protein; See PMID:20190049 for expression data; similar to GP:15159638; identified by sequence similarity; putative. | This gene is aparrently the initiating component of a non-ribosomal peptide synthetase (due to the presence of an initial non-amino acid adenylation/ligase domain) and is most likely associated with the following gene which appears to be a terminating component. This gene contains a thiolation domain as well as one complete amino acid activation, thiolation and condensation domain modules which appears to be specific for serine according to the prediction algorithm at http://raynam.chm.jhu.edu/; nrps/index2.html. Taken together these two genes appear to direct the biosynthesis of a pre [...] | 0.988 |
AAO55654.1 | AAO57967.1 | PSPTO_2137 | PSPTO_4519 | MbtH-like protein; See PMID:20190049 for expression data; similar to GP:15159638; identified by sequence similarity; putative. | This gene is aparrently the terminal component of a non-ribosomal peptide synthetase (due to the presence of the terminal thioesterase domain) and is most likely associated with the previous gene which appears to be a initiating component. This gene contains three complete amino acid activation, thiolation and condensation domain modules and appears to be specific for glycine, an unidentified amino acid and serine according to the prediction algorithm at http://raynam.chm.jhu.edu/; nrps/index2.html. Taken together these two genes appear to direct the biosynthesis of a previously undesc [...] | 0.999 |
AAO55654.1 | cfa6 | PSPTO_2137 | PSPTO_4686 | MbtH-like protein; See PMID:20190049 for expression data; similar to GP:15159638; identified by sequence similarity; putative. | Coronafacic acid polyketide synthase I; This gene is the first of two multimodular polyketide synthetases involved in the biosynthesis of coronafacic acid. This synthetase is proposed to receive CPC (2-carboxy-2-cyclopentenone) from an acyl carrier protein (cfa1), it then adds a buyrate group and then completely reduces the ketone of the (former) carboxylate group. The resulting product is then passed to the second polyketide synthetase (cfa7); similar to GP:13346874; identified by sequence similarity; putative; see PMID:20190049 for expression data; This gene is the first of two multi [...] | 0.917 |
AAO55654.1 | cfa7 | PSPTO_2137 | PSPTO_4687 | MbtH-like protein; See PMID:20190049 for expression data; similar to GP:15159638; identified by sequence similarity; putative. | Coronafacic acid polyketide synthetase II; This gene is the second of two multimodular polyketide synthetases involved in the biosynthesis of coronafacic acid. This synthetase is proposed to receive CPE (2-[1-oxo-2-cyclopenten-2-ylmethyl]butanoic acid) from the first synthetase, Cpe6. It then adds one final acetate group, catalyzes the cyclization of the second ring and converts a ketone to a double bond. The product is released by a terminal thioesterase domain; similar to GP:13162634; identified by sequence similarity; putative; see PMID:20190049 for expression data; This gene is the [...] | 0.921 |
AAO55654.1 | cmaA | PSPTO_2137 | PSPTO_4709 | MbtH-like protein; See PMID:20190049 for expression data; similar to GP:15159638; identified by sequence similarity; putative. | Coronamic acid synthetase CmaA; Non-ribosomal peptide synthetase with adenylation and thiolation domains; reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis; see PMID: 14679222; see PMID:20190049 for expression data; non-ribosomal peptide synthetase with adenylation and thiolation domains, reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis, see PMID: 14679222. | 0.999 |
AAO55654.1 | irp4 | PSPTO_2137 | PSPTO_2598 | MbtH-like protein; See PMID:20190049 for expression data; similar to GP:15159638; identified by sequence similarity; putative. | Yersiniabactin synthetase, thioesterase component; Possibly involved in the release of an intermediate product see PMID:20190049 for expression data; similar to pyochelin, since the terminal yersiniabactin synthetase has its own thioesterase domain; see PMID:20190049 for expression data; similar to GP:3818607; identified by sequence similarity; putative. | 0.818 |
AAO55654.1 | mgoA | PSPTO_2137 | PSPTO_5457 | MbtH-like protein; See PMID:20190049 for expression data; similar to GP:15159638; identified by sequence similarity; putative. | Ornithine acetyl transferase inhibitor; This enzyme consists of an amino acid activation and ligation domain followed by a thiolation domaintypical of non-ribosomal peptide synthetases; similar to the ornithine acetyl transferase inhibitor mangotoxin; see PMID:17506328. | 0.983 |
AAO55654.1 | syfB | PSPTO_2137 | PSPTO_2830 | MbtH-like protein; See PMID:20190049 for expression data; similar to GP:15159638; identified by sequence similarity; putative. | Non-ribosomal peptide synthetase SyfB; This gene consists of five complete condensation, adenylation, thiolation domain modules followed by two thioesterase domains. The adenylation domains are specific for leucine, threonine, valine, leucine and leucine; together with PSPTO_2829 codes for proteins involved in production of lipopeptide syringofactins. See PMID:17601782. | 0.993 |
AAO57966.1 | AAO55651.1 | PSPTO_4518 | PSPTO_2134 | This gene is aparrently the initiating component of a non-ribosomal peptide synthetase (due to the presence of an initial non-amino acid adenylation/ligase domain) and is most likely associated with the following gene which appears to be a terminating component. This gene contains a thiolation domain as well as one complete amino acid activation, thiolation and condensation domain modules which appears to be specific for serine according to the prediction algorithm at http://raynam.chm.jhu.edu/; nrps/index2.html. Taken together these two genes appear to direct the biosynthesis of a pre [...] | Pyoverdine synthetase, thioesterase component; Presumed to be involved in the biosynthesis of pyoverdine due to proximity to the rest of the pyoverdine biosynthetic gene cluster. Possibly acts to release the pyoverdine chromophore precursor from PvsA; see PMID:20190049 for expression data; similar to GP:9948471; identified by sequence similarity; putative. | 0.895 |
AAO57966.1 | AAO55654.1 | PSPTO_4518 | PSPTO_2137 | This gene is aparrently the initiating component of a non-ribosomal peptide synthetase (due to the presence of an initial non-amino acid adenylation/ligase domain) and is most likely associated with the following gene which appears to be a terminating component. This gene contains a thiolation domain as well as one complete amino acid activation, thiolation and condensation domain modules which appears to be specific for serine according to the prediction algorithm at http://raynam.chm.jhu.edu/; nrps/index2.html. Taken together these two genes appear to direct the biosynthesis of a pre [...] | MbtH-like protein; See PMID:20190049 for expression data; similar to GP:15159638; identified by sequence similarity; putative. | 0.988 |